The histology of brain tumors for 67 331 children and 671 085 adults diagnosed in 60 countries during 2000-2014: a global, population-based study (CONCORD-3).
Details
Serval ID
serval:BIB_AD4C9B7391CB
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The histology of brain tumors for 67 331 children and 671 085 adults diagnosed in 60 countries during 2000-2014: a global, population-based study (CONCORD-3).
Journal
Neuro-oncology
Working group(s)
CONCORD Working Group
Contributor(s)
Bouzbid S., Hamdi-Chérif M., Zaidi Z., Meguenni K., Regagba D., Bayo S., Cheick Bougadari T., Manraj S.S., Bendahhou K., Ladipo A., Ogunbiyi O.J., Ramaliba T., Somdyala NIM, Chaplin M.A., Moreno F., Calabrano G.H., Espinola S.B., Carballo Quintero B., Fita R., Laspada W.D., Ibañez S.G., Lima C.A., Mafra da Costa A., De Souza PCF, Del Pino K., Laporte C., Curado M.P., de Oliveira J.C., Veneziano CLA, Veneziano D.B., Latorre MRDO, Tanaka L.F., Rebelo M.S., Santos M.O., Azevedo E Silva G., Galaz J.C., Aparicio Aravena M., Sanhueza Monsalve J., Herrmann D.A., Vargas S., Herrera V.M., Uribe C.J., Bravo L.E., Garcia L.S., Arias-Ortiz N.E., Morantes D., Jurado D.M., Yépez Chamorro M.C., Delgado S., Ramirez M., Galán Alvarez Y.H., Torres P., Martínez-Reyes F., Jaramillo L., Quinto R., Castillo J., Mendoza M., Cueva P., Yépez J.G., Bhakkan B., Deloumeaux J., Joachim C., Macni J., Carrillo R., Shalkow Klincovstein J., Rivera Gomez R., Perez P., Poquioma E., Tortolero-Luna G., Zavala D., Alonso R., Barrios E., Eckstrand A., Nikiforuk C., Woods R.R., Noonan G., Turner D., Kumar E., Zhang B., McCrate F.R., Ryan S., MacIntyre M., Saint-Jacques N., Anam A., De P., McClure C.A., Vriends K.A., Bertrand C., Latreille J., Kozie S., Stuart-Panko H., Freeman T., George J.T., Avila R.M., O'Brien D.K., Holt A., Almon L., Kwong S., Morris C., Rycroft R., Mueller L., Phillips C.E., Brown H., Cromartie B., Schwartz A.G., Vigneau F., Levin G.M., Wohler B., Bayakly R., Ward K.C., Gomez S.L., McKinley M., Cress R., Green M.D., Miyagi K., Johnson C.J., Ruppert L.P., Bentler S., Charlton M.E., Huang B., Tucker T.C., Deapen D., Liu L., Hsieh M.C., Wu X.C., Schwenn M., Stern K., Gershman S.T., Knowlton R.C., Alverson G., Weaver T., Bushhouse S., Rogers D.B., Jackson-Thompson J., Lemons D., Zimmerman H.J., Hood M., Roberts-Johnson J., Riddle B., Rees J.R., Pawlish K.S., Stroup A., Key C., Wiggins C., Kahn A.R., Schymura M.J., Radhakrishnan S., Rao C., Giljahn L.K., Slocumb R.M., Feld A., Aird K.G., Beran T., Rubertone J.J., Slack S.J., Oh J., Janes T.A., Schwartz S.M., Chiodini S., Hurley D.M., Whiteside M.A., Rai S., Williams M.A., Herget K., Sweeney C., Johnson A.T., Keitheri Cheteri M.B., Migliore Santiago P., Blankenship S.E., Farley S., Borchers R., Malicki R., Espinoza J., Grandpre J., Weir H.K., Wilson R., Edwards B.K., Mariotto A., Wang N., Yang L., Chen J.S., Zhou Y., He Y.T., Song G.H., Gu X.P., Mei D., Mu H.J., Ge H.M., Wu T.H., Li Y.Y., Zhao D.L., Jin F., Zhang J.H., Zhu F.D., Junhua Q., Yang Y.L., Jiang C.X., Biao W., Wang J., Li Q.L., Yi H., Zhou X., Dong J., Li W., Fu F.X., Liu S.Z., Chen J.G., Zhu J., Li Y.H., Lu Y.Q., Fan M., Huang S.Q., Guo G.P., Zhaolai H., Wei K., Chen W.Q., Wei W., Zeng H., Demetriou A.V., Mang W.K., Ngan K.C., Kataki A.C., Krishnatreya M., Jayalekshmi P.A., Sebastian P., George P.S., Mathew A., Nandakumar A., Malekzadeh R., Roshandel G., Keinan-Boker L., Silverman B.G., Koyanagi Y., Ito H., Sato M., Tobori F., Nakata I., Teramoto N., Hattori M., Kaizaki Y., Moki F., Sugiyama H., Utada M., Nishimura M., Yoshida K., Kurosawa K., Nemoto Y., Narimatsu H., Sakaguchi M., Kanemura S., Naito M., Narisawa R., Miyashiro I., Nakata K., Maeda A., Sato S., Oki I., Fukushima N., Shibata A., Iwasa K., Ono C., Matsuda T., Nimri O., Jung K.W., Won Y.J., Alawadhi E., Elbasmi A., Ab Manan A., Adam F., Nansalmaa E., Tudev U., Ochir C., Al Khater A.M., El Mistiri M.M., Lim G.H., Teo Y.Y., Chiang C.J., Lee W.C., Buasom R., Sangrajrang S., Suwanrungruang K., Vatanasapt P., Daoprasert K., Pongnikorn D., Leklob A., Sangkitipaiboon S., Geater S.L., Sriplung H., Ceylan O., Kög I., Dirican O., Köse T., Gurbuz T., Karaşahin F.E., Turhan D., Aktaş U., Halat Y., Eser S., Yakut C.I., Altinisik M., Cavusoglu Y., Türkköylü A., Üçüncü N., Hackl M., Zborovskaya A.A., Aleinikova O.V., Henau K., Van Eycken L., Valerianova Z., Yordanova M.R., Šekerija M., Dušek L., Zvolský M., Steinrud Mørch L., Storm H., Wessel Skovlund C., Innos K., Mägi M., Malila N., Seppä K., Jégu J., Velten M., Cornet E., Troussard X., Bouvier A.M., Guizard A.V., Bouvier V., Launoy G., Arveux P., Maynadié M., Mounier M., Woronoff A.S., Daoulas M., Robaszkiewicz M., Clavel J., Goujon S., Lacour B., Baldi I., Pouchieu C., Amadeo B., Coureau G., Orazio S., Monnereau A., Preux P.M., Rharbaoui F., Marrer E., Trétarre B., Colonna M., Delafosse P., Plouvier S., Cowppli-Bony A., Molinié F., Bara S., Ganry O., Lapôtre-Ledoux B., Grosclaude P., Bossard N., Uhry Z., Estève J., Stabenow R., Wilsdorf-Köhler H., Eberle A., Luttmann S., Löhden I., Nennecke A.L., Kieschke J., Sirri E., Justenhoven C., Zeissig S.R., Holleczek B., Eisemann N., Katalinic A., Asquez R.A., Kumar V., Petridou E., Ólafsdóttir E.J., Tryggvadóttir L., Clough-Gorr K., Walsh P.M., Sundseth H., Mazzoleni G., Vittadello F., Coviello E., Cuccaro F., Galasso R., Sampietro G., Giacomin A., Magoni M., Ardizzone A., D'Argenzio A., Castaing M., Grosso G., Lavecchia A.M., Sutera Sardo A., Gola G., Gatti L., Ricci P., Ferretti S., Dal Maso L., Serraino D., Celesia M.V., Filiberti R.A., Pannozzo F., Melcarne A., Quarta F., Andreano A., Russo A.G., Carrozzi G., Cirilli C., Cavalieri d'Oro L., Rognoni M., Fusco M., Vitale M.F., Usala M., Cusimano R., Mazzucco W., Michiara M., Sgargi P., Boschetti L., Chiaranda G., Seghini P., Maule M.M., Merletti F., Tumino R., Mancuso P., Vicentini M., Cassetti T., Sassatelli R., Falcini F., Giorgetti S., Caiazzo A.L., Cavallo R., Cesaraccio R., Pirino D.R., Bella F., Madeddu A., Fanetti A.C., Maspero S., Carone S., Mincuzzi A., Candela G., Scuderi T., Gentilini M.A., Piffer S., Rosso S., Barchielli A., Caldarella A., Bianconi F., Stracci F., Contiero P., Tagliabue G., Rugge M., Zorzi M., Beggiato S., Brustolin A., Gatta G., Rugge M., De Angelis R., Zanetti R., Maurina A., Oniščuka M., Mousavi M., Lipunova N., Vincerževskienė I., Agius D., Calleja N., Siesling S., Visser O., Larønningen S., Møller B., Dyzmann-Sroka A., Trojanowski M., Góźdź S., Mierzwa T., Molong L., Rachtan J., Szewczyk S., Błaszczyk J., Kępska K., Kościańska B., Amunicka R., Ostrowski A., Zwierko M., Kaczmarek W., Maksimowicz K.M., Purwin-Porowska E., Reca E., Wójcik-Tomaszewska J., Czajkowska E., Motnyk M., Grądalska-Lampart M., Radziszewska A.U., Gos A., Talerczyk M., Wyborska M., Didkowska J.A., Wojciechowska U., Bielska-Lasota M., Forjaz de Lacerda G., Rego R.A., Carrito B., Pais A., Bento MJAT, Rodrigues J.R., Mayer-da-Silva A., Miranda A., Blaga L.M., Coza D., Valkov M.Y., Gusenkova L., Lazarevich O., Prudnikova O., Vjushkov D.M., Egorova A.G., Orlov A.E., Kudyakov L.A., Pikalova L.V., Adamcik J., Safaei Diba C., Primic-Žakelj M., Zadnik V., Gil L., Lopez de Munain A., Herrera A.A., Rojas D., Chillarón R.J., Navarro AIM, Marcos-Gragera R., Vilardell Gil M.L., Molina E., Sánchez Perez M.J., Franch Sureda P., Ramos Montserrat M., Chirlaque M.D., Navarro C., Ardanaz E., Guevara M., Cañete-Nieto A., Peris-Bonet R., Carulla M., Galceran J., Almela F., Sabater C., Khan S., Pettersson D., Dickman P., Staehelin K., Struchen B., Egger Hayoz C., Bouchardy C., Schaffar R., Rössle M., Mousavi S.M., Bulliard J.L., Maspoli-Conconi M., Herrmann C., Kuehni C.E., Redmond S.M., Bordoni A., Ortelli L., Chiolero A., Konzelmann I., Matthes K.L., Rohrmann S., Broggio J., Rashbass J., Fitzpatrick D., Gavin A., Clark D.I., Deas A.J., Huws D.W., Allemani C., Coleman M.P., Di Carlo V., Girardi F., Matz M., Minicozzi P., Montel L., Nikšić M., Ssenyonga N., Stephens R., Stiller C., Chalker E., Smith M., Walton R., You H., Qin Li S., Dugdale S., Moore J., Philpot S., Pfeiffer R., Thomas H., Stokes B.C., Venn A., Farrugia H., Thursfield V., Dowling J., Currow D., Fowler C., Lewis C.
ISSN
1523-5866 (Electronic)
ISSN-L
1522-8517
Publication state
Published
Issued date
01/10/2021
Peer-reviewed
Oui
Volume
23
Number
10
Pages
1765-1776
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
Global variations in survival for brain tumors are very wide when all histological types are considered together. Appraisal of international differences should be informed by the distribution of histology, but little is known beyond Europe and North America.
The source for the analysis was the CONCORD database, a program of global surveillance of cancer survival trends, which includes the tumor records of individual patients from more than 300 population-based cancer registries. We considered all patients aged 0-99 years who were diagnosed with a primary brain tumor during 2000-2014, whether malignant or nonmalignant. We presented the histology distribution of these tumors, for patients diagnosed during 2000-2004, 2005-2009, and 2010-2014.
Records were submitted from 60 countries on 5 continents, 67 331 for children and 671 085 for adults. After exclusion of irrelevant morphology codes, the final study population comprised 60 783 children and 602 112 adults. Only 59 of 60 countries covered in CONCORD-3 were included because none of the Mexican records were eligible. We defined 12 histology groups for children, and 11 for adults. In children (0-14 years), the proportion of low-grade astrocytomas ranged between 6% and 50%. Medulloblastoma was the most common subtype in countries where low-grade astrocytoma was less commonly reported. In adults (15-99 years), the proportion of glioblastomas varied between 9% and 69%. International comparisons were made difficult by wide differences in the proportion of tumors with unspecified histology, which accounted for up to 52% of diagnoses in children and up to 65% in adults.
To our knowledge, this is the first account of the global histology distribution of brain tumors, in children and adults. Our findings provide insights into the practices and the quality of cancer registration worldwide.
The source for the analysis was the CONCORD database, a program of global surveillance of cancer survival trends, which includes the tumor records of individual patients from more than 300 population-based cancer registries. We considered all patients aged 0-99 years who were diagnosed with a primary brain tumor during 2000-2014, whether malignant or nonmalignant. We presented the histology distribution of these tumors, for patients diagnosed during 2000-2004, 2005-2009, and 2010-2014.
Records were submitted from 60 countries on 5 continents, 67 331 for children and 671 085 for adults. After exclusion of irrelevant morphology codes, the final study population comprised 60 783 children and 602 112 adults. Only 59 of 60 countries covered in CONCORD-3 were included because none of the Mexican records were eligible. We defined 12 histology groups for children, and 11 for adults. In children (0-14 years), the proportion of low-grade astrocytomas ranged between 6% and 50%. Medulloblastoma was the most common subtype in countries where low-grade astrocytoma was less commonly reported. In adults (15-99 years), the proportion of glioblastomas varied between 9% and 69%. International comparisons were made difficult by wide differences in the proportion of tumors with unspecified histology, which accounted for up to 52% of diagnoses in children and up to 65% in adults.
To our knowledge, this is the first account of the global histology distribution of brain tumors, in children and adults. Our findings provide insights into the practices and the quality of cancer registration worldwide.
Keywords
Adult, Astrocytoma, Brain Neoplasms/epidemiology, Child, Databases, Factual, Europe, Humans, Registries, International Classification of Diseases, epidemiological study, health care disparities, histology, population-based cancer registries, primary brain tumor
Pubmed
Web of science
Open Access
Yes
Create date
15/06/2023 9:56
Last modification date
16/06/2023 6:56
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