Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up.

Nguyen, T.N.; Qureshi, M.M.; Klein, P.; Yamagami, H.; Mikulik, R.; Czlonkowska, A.; Abdalkader, M.; Sedova, P.; Sathya, A.; Lo, H.C.; Mansour, O.Y.; Vanguru, H.R.; Lesaine, E.; Tsivgoulis, G.; Loochtan, A.I.; Demeestere, J.; Uchino, K.; Inoa, V.; Goyal, N.; Charidimou, A.; Siegler, J.E.; Yaghi, S.; Aguiar de Sousa, D.; Mohammaden, M.H.; Haussen, D.C.; Kristoffersen, E.S.; Lereis, V.P.; Scollo, S.D.; Campbell, BCV; Ma, A.; Thomas, J.O.; Parsons, M.W.; Singhal, S.; Slater, L.A.; Tomazini Martins, R.; Enzinger, C.; Gattringer, T.; Rahman, A.; Bonnet, T.; Ligot, N.; De Raedt, S.; Lemmens, R.; Vanacker, P.; Vandervorst, F.; Conforto, A.B.; Hidalgo, RCT; de Oliveira Neves, L.; Martins, R.T.; Mora Cuervo, D.L.; Rebello, L.C.; Santiago, I.B.; Lameirinhas da Silva, I.; Sakelarova, T.; Kalpachki, R.; Alexiev, F.; Catanese, L.; Cora, E.A.; Goyal, M.; Hill, M.D.; Kelly, M.E.; Khosravani, H.; Lavoie, P.; Peeling, L.; Pikula, A.; Rivera, R.; Chen, H.S.; Chen, Y.; Huo, X.; Miao, Z.; Yang, S.; Bedekovic, M.R.; Bralic, M.; Budincevic, H.; Corredor-Quintero, A.B.; Lara-Sarabia, O.E.; Cabal, M.; Tenora, D.; Fibrich, P.; Herzig, R.; Hlaváčová, H.; Hrabanovska, E.; Hlinovsky, D.; Jurak, L.; Kadlcikova, J.; Karpowicz, I.; Klecka, L.; Kovar, M.; Lauer, D.; Neumann, J.; Palouskova, H.; Reiser, M.; Rekova, P.; Rohan, V.; Skoda, O.; Škorňa, M.; Sobotková, L.; Sramek, M.; Zakova, L.; Christensen, H.; Drenck, N.; Iversen, H.K.; Truelsen, T.C.; Wienecke, T.; Sobh, K.; Ylikotila, P.; Alpay, K.; Strbian, D.; Bernady, P.; Casenave, P.; Dan, M.; Faucheux, J.M.; Gentric, J.C.; Magro, E.; Sabben, C.; Reiner, P.; Rouanet, F.; Bohmann, F.O.; Boskamp, S.; Mbroh, J.; Nagel, S.; Nolte, C.H.; Ringleb, P.A.; Rosenkranz, M.; Poli, S.; Thomalla, G.; Karapanayiotides, T.; Koutroulou, I.; Kargiotis, O.; Palaiodimou, L.; Barrientos Guerra, J.D.; Huded, V.; Menon, B.; Nagendra, S.; Prajapati, C.; Sylaja, P.N.; Krishna Pramana, N.A.; Sani, A.F.; Ghoreishi, A.; Farhoudi, M.; Hokmabadi, E.S.; Raya, T.A.; Kalmanovich, S.A.; Ronen, L.; Sabetay, S.I.; Acampa, M.; Adami, A.; Castellan, L.; Longoni, M.; Ornello, R.; Renieri, L.; Bigliani, C.R.; Romoli, M.; Sacco, S.; Salmaggi, A.; Sangalli, D.; Zini, A.; Doijiri, R.; Fukuda, H.; Fujinaka, T.; Fujita, K.; Imamura, H.; Sakai, N.; Kanamaru, T.; Kimura, N.; Kono, R.; Miyake, K.; Sakaguchi, M.; Sakai, K.; Sonoda, K.; Todo, K.; Miyashita, F.; Tokuda, N.; Matsumaru, Y.; Matsumoto, S.; Ohara, N.; Shindo, S.; Takenobu, Y.; Yoshimoto, T.; Toyoda, K.; Uwatoko, T.; Yagita, Y.; Yamada, T.; Yamamoto, N.; Yamamoto, R.; Yazawa, Y.; Sugiura, Y.; Waweru, P.K.; Baek, J.H.; Lee, S.B.; Seo, K.D.; Sohn, S.I.; Arsovska, A.A.; Chan, Y.C.; Wan Zaidi, W.A.; Jaafar, A.S.; Gongora-Rivera, F.; Martinez-Marino, M.; Infante-Valenzuela, A.; Groppa, S.; Leahu, P.; Coutinho, J.M.; Rinkel, L.A.; Dippel, DWJ; van Dam-Nolen, DHK; Ranta, A.; Wu, T.Y.; Adebayo, T.T.; Bello, A.H.; Nwazor, E.O.; Sunmonu, T.A.; Wahab, K.W.; Ronning, O.M.; Sandset, E.C.; Al Hashmi, A.M.; Ahmad, S.; Rashid, U.; Rodriguez-Kadota, L.; Vences, M.Á.; Yalung, P.M.; Hao Dy, J.S.; Pineda-Franks, M.C.; Co, C.O.; Brola, W.; Debiec, A.; Dorobek, M.; Karlinski, M.A.; Labuz-Roszak, B.M.; Lasek-Bal, A.; Sienkiewicz-Jarosz, H.; Staszewski, J.; Sobolewski, P.; Wiacek, M.; Zielinska-Turek, J.; Araujo, A.P.; Rocha, M.; Castro, P.; Cruz, V.T.; Ferreira, P.V.; Ferreira, P.; Nunes, A.P.; Fonseca, L.; Marto, J.P.; Pinho E Melo, T.; Rodrigues, M.; Silva, M.L.; Dimitriade, A.; Falup-Pecurariu, C.; Hamid, M.A.; Venketasubramanian, N.; Krastev, G.; Mako, M.; Ayo-Martin, O.; Hernández-Fernández, F.; Blasco, J.; Rodríguez-Vázquez, A.; Cruz-Culebras, A.; Moniche, F.; Montaner, J.; Perez-Sanchez, S.; García Sánchez, M.J.; Guillán Rodríguez, M.; Jood, K.; Nordanstig, A.; Mazya, M.V.; Moreira, TTP; Bernava, G.; Beyeler, M.; Bolognese, M.; Carrera, E.; Dobrocky, T.; Karwacki, G.M.; Keller, E.; Hsieh, C.Y.; Boonyakarnkul, S.; Churojana, A.; Aykac, O.; Ozdemir, A.Ã.; Bajrami, A.; Senadim, S.; Hussain, S.I.; John, S.; Banerjee, S.; Kwan, J.; Krishnan, K.; Lenthall, R.; Matthews, A.; Wong, K.; Zhang, L.; Altschul, D.; Asif, K.S.; Bahiru, Z.; Below, K.; Biller, J.; Ruland, S.; Chaudry, S.A.; Chen, M.; Chebl, A.; Cibulka, J.; Cistrunk, L.; Clark, J.; Colasurdo, M.; Czap, A.; de Havenon, A.; D'Amato, S.; Dharmadhikari, S.; Grimmett, K.B.; Dmytriw, A.A.; Etherton, M.R.; Ezepue, C.; Farooqui, M.; Feske, S.K.; Fink, L.; Gasimova, U.; Guzik, A.K.; Hakemi, M.; Hovingh, M.; Khan, M.; Jillela, D.; Kan, P.T.; Khatri, R.; Khawaja, A.M.; Khoury, N.N.; Kiley, N.L.; Kim, B.S.; Kolikonda, M.K.; Kuhn, A.L.; Lara, S.; Linares, G.; Linfante, I.; Lukovits, T.G.; Lycan, S.; Male, S.S.; Maali, L.; Mancin, J.; Masoud, H.; Mohamed, G.A.; Monteiro, A.; Nahab, F.; Nalleballe, K.; Ortega-Gutierrez, S.; Puri, A.S.; Radaideh, Y.; Rahangdale, R.H.; Rai, A.; Ramakrishnan, P.; Reddy, A.B.; Rojas-Soto, D.M.; Romero, J.R.; Rost, N.S.; Rothstein, A.; Omran, S.S.; Sheth, S.A.; Siddiqui, A.H.; Starosciak, A.K.; Tarlov, N.E.; Taylor, R.A.; Wang, M.J.; Wolfe, J.; Wong, K.H.; Le, H.V.; Nguyen, Q.V.; Pham, T.N.; Nguyen, T.T.; Phan, H.T.; Ton, M.D.; Fischer, U.; Michel, P.; Strambo, D.; Martins, S.O.; Zaidat, O.O.; Nogueira, R.G.

doi:10.1212/WNL.0000000000201426

Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up.

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Serval ID

serval:BIB_AA4B5072FB7F

Type

Article: article from journal or magazin.

Collection

Publications

Institution

UNIL/CHUV

Title

Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up.

Journal

Neurology

Author(s)

Nguyen T.N., Qureshi M.M., Klein P., Yamagami H., Mikulik R., Czlonkowska A., Abdalkader M., Sedova P., Sathya A., Lo H.C., Mansour O.Y., Vanguru H.R., Lesaine E., Tsivgoulis G., Loochtan A.I., Demeestere J., Uchino K., Inoa V., Goyal N., Charidimou A., Siegler J.E., Yaghi S., Aguiar de Sousa D., Mohammaden M.H., Haussen D.C., Kristoffersen E.S., Lereis V.P., Scollo S.D., Campbell BCV, Ma A., Thomas J.O., Parsons M.W., Singhal S., Slater L.A., Tomazini Martins R., Enzinger C., Gattringer T., Rahman A., Bonnet T., Ligot N., De Raedt S., Lemmens R., Vanacker P., Vandervorst F., Conforto A.B., Hidalgo RCT, de Oliveira Neves L., Martins R.T., Mora Cuervo D.L., Rebello L.C., Santiago I.B., Lameirinhas da Silva I., Sakelarova T., Kalpachki R., Alexiev F., Catanese L., Cora E.A., Goyal M., Hill M.D., Kelly M.E., Khosravani H., Lavoie P., Peeling L., Pikula A., Rivera R., Chen H.S., Chen Y., Huo X., Miao Z., Yang S., Bedekovic M.R., Bralic M., Budincevic H., Corredor-Quintero A.B., Lara-Sarabia O.E., Cabal M., Tenora D., Fibrich P., Herzig R., Hlaváčová H., Hrabanovska E., Hlinovsky D., Jurak L., Kadlcikova J., Karpowicz I., Klecka L., Kovar M., Lauer D., Neumann J., Palouskova H., Reiser M., Rekova P., Rohan V., Skoda O., Škorňa M., Sobotková L., Sramek M., Zakova L., Christensen H., Drenck N., Iversen H.K., Truelsen T.C., Wienecke T., Sobh K., Ylikotila P., Alpay K., Strbian D., Bernady P., Casenave P., Dan M., Faucheux J.M., Gentric J.C., Magro E., Sabben C., Reiner P., Rouanet F., Bohmann F.O., Boskamp S., Mbroh J., Nagel S., Nolte C.H., Ringleb P.A., Rosenkranz M., Poli S., Thomalla G., Karapanayiotides T., Koutroulou I., Kargiotis O., Palaiodimou L., Barrientos Guerra J.D., Huded V., Menon B., Nagendra S., Prajapati C., Sylaja P.N., Krishna Pramana N.A., Sani A.F., Ghoreishi A., Farhoudi M., Hokmabadi E.S., Raya T.A., Kalmanovich S.A., Ronen L., Sabetay S.I., Acampa M., Adami A., Castellan L., Longoni M., Ornello R., Renieri L., Bigliani C.R., Romoli M., Sacco S., Salmaggi A., Sangalli D., Zini A., Doijiri R., Fukuda H., Fujinaka T., Fujita K., Imamura H., Sakai N., Kanamaru T., Kimura N., Kono R., Miyake K., Sakaguchi M., Sakai K., Sonoda K., Todo K., Miyashita F., Tokuda N., Matsumaru Y., Matsumoto S., Ohara N., Shindo S., Takenobu Y., Yoshimoto T., Toyoda K., Uwatoko T., Yagita Y., Yamada T., Yamamoto N., Yamamoto R., Yazawa Y., Sugiura Y., Waweru P.K., Baek J.H., Lee S.B., Seo K.D., Sohn S.I., Arsovska A.A., Chan Y.C., Wan Zaidi W.A., Jaafar A.S., Gongora-Rivera F., Martinez-Marino M., Infante-Valenzuela A., Groppa S., Leahu P., Coutinho J.M., Rinkel L.A., Dippel DWJ, van Dam-Nolen DHK, Ranta A., Wu T.Y., Adebayo T.T., Bello A.H., Nwazor E.O., Sunmonu T.A., Wahab K.W., Ronning O.M., Sandset E.C., Al Hashmi A.M., Ahmad S., Rashid U., Rodriguez-Kadota L., Vences M.Á., Yalung P.M., Hao Dy J.S., Pineda-Franks M.C., Co C.O., Brola W., Debiec A., Dorobek M., Karlinski M.A., Labuz-Roszak B.M., Lasek-Bal A., Sienkiewicz-Jarosz H., Staszewski J., Sobolewski P., Wiacek M., Zielinska-Turek J., Araujo A.P., Rocha M., Castro P., Cruz V.T., Ferreira P.V., Ferreira P., Nunes A.P., Fonseca L., Marto J.P., Pinho E Melo T., Rodrigues M., Silva M.L., Dimitriade A., Falup-Pecurariu C., Hamid M.A., Venketasubramanian N., Krastev G., Mako M., Ayo-Martin O., Hernández-Fernández F., Blasco J., Rodríguez-Vázquez A., Cruz-Culebras A., Moniche F., Montaner J., Perez-Sanchez S., García Sánchez M.J., Guillán Rodríguez M., Jood K., Nordanstig A., Mazya M.V., Moreira TTP, Bernava G., Beyeler M., Bolognese M., Carrera E., Dobrocky T., Karwacki G.M., Keller E., Hsieh C.Y., Boonyakarnkul S., Churojana A., Aykac O., Ozdemir A.Ã., Bajrami A., Senadim S., Hussain S.I., John S., Banerjee S., Kwan J., Krishnan K., Lenthall R., Matthews A., Wong K., Zhang L., Altschul D., Asif K.S., Bahiru Z., Below K., Biller J., Ruland S., Chaudry S.A., Chen M., Chebl A., Cibulka J., Cistrunk L., Clark J., Colasurdo M., Czap A., de Havenon A., D'Amato S., Dharmadhikari S., Grimmett K.B., Dmytriw A.A., Etherton M.R., Ezepue C., Farooqui M., Feske S.K., Fink L., Gasimova U., Guzik A.K., Hakemi M., Hovingh M., Khan M., Jillela D., Kan P.T., Khatri R., Khawaja A.M., Khoury N.N., Kiley N.L., Kim B.S., Kolikonda M.K., Kuhn A.L., Lara S., Linares G., Linfante I., Lukovits T.G., Lycan S., Male S.S., Maali L., Mancin J., Masoud H., Mohamed G.A., Monteiro A., Nahab F., Nalleballe K., Ortega-Gutierrez S., Puri A.S., Radaideh Y., Rahangdale R.H., Rai A., Ramakrishnan P., Reddy A.B., Rojas-Soto D.M., Romero J.R., Rost N.S., Rothstein A., Omran S.S., Sheth S.A., Siddiqui A.H., Starosciak A.K., Tarlov N.E., Taylor R.A., Wang M.J., Wolfe J., Wong K.H., Le H.V., Nguyen Q.V., Pham T.N., Nguyen T.T., Phan H.T., Ton M.D., Fischer U., Michel P., Strambo D., Martins S.O., Zaidat O.O., Nogueira R.G.

Working group(s)

and the SVIN COVID-19 Global Stroke Registry

ISSN

1526-632X (Electronic)

ISSN-L

0028-3878

Publication state

Published

Issued date

24/01/2023

Peer-reviewed

Oui

Volume

100

Number

Pages

e408-e421

Language

english

Notes

Publication types: Clinical Study ; Journal Article
Publication Status: ppublish

Abstract

Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020).
We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases.
There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1-6.9]; p < 0.0001). ICH volumes declined from 29,585 to 28,156 (4.8% [5.1-4.6]; p < 0.0001) and IVT volume from 24,584 to 23,077 (6.1% [6.4-5.8]; p < 0.0001). Larger declines were observed at high-volume compared with low-volume centers (all p < 0.0001). There was no significant change in mechanical thrombectomy volumes (0.7% [0.6-0.9]; p = 0.49). Stroke was diagnosed in 1.3% [1.31-1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82-2.97], 5,656/195,539) of all stroke hospitalizations.
There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year.
This study is registered under NCT04934020.

Keywords

Humans, Brain Ischemia/therapy, COVID-19/epidemiology, COVID-19/therapy, Follow-Up Studies, Intracranial Hemorrhages, Pandemics, Retrospective Studies, SARS-CoV-2, Stroke/epidemiology, Stroke/therapy, Stroke/diagnosis, Stroke Volume, Thrombectomy, Thrombolytic Therapy/methods, Treatment Outcome

OAI-PMH

oai:serval.unil.ch:BIB_AA4B5072FB7F

DOI

10.1212/WNL.0000000000201426

Pubmed

36257718

Web of science

000927965000020

Open Access

Yes

Create date

24/10/2022 12:18