Cutaneous human papillomavirus in head and neck squamous cell carcinomas.
Details
Serval ID
serval:BIB_A9D05A92DE4A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cutaneous human papillomavirus in head and neck squamous cell carcinomas.
Journal
Cancer Investigation
ISSN
1532-4192 (Electronic)
ISSN-L
0735-7907
Publication state
Published
Issued date
2009
Volume
27
Number
7
Pages
781-787
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
To evaluate the prevalence and meaning of cutaneous human papillomavirus (HPV) types in HNSCC 51 patients were analyzed for the prevalence of cutaneous as well as mucosal HPV. HPV DNA was demonstrated in 18 (35%) of 51 tumors. The majority of these HPV types belong to so-called cutaneous HPV types, whereas only HPV 6 and HPV 16 were from the mucosal HPV types. A possible role for cutaneous HPV types as co-factors in the oncogenesis of HNSCC remains to be elucidated and may be relevant for future strategies of cancer prevention.
Keywords
Aged, Alcohol Drinking/epidemiology, Alphapapillomavirus/classification, Alphapapillomavirus/isolation & purification, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Carboplatin/administration & dosage, Carcinoma, Squamous Cell/drug therapy, Carcinoma, Squamous Cell/radiotherapy, Cell Transformation, Viral, Combined Modality Therapy, DNA Probes, HPV, DNA, Viral/analysis, Disease-Free Survival, Dose Fractionation, Fluorouracil/administration & dosage, Head and Neck Neoplasms/drug therapy, Head and Neck Neoplasms/radiotherapy, Humans, Male, Middle Aged, Mucous Membrane/virology, Organ Specificity, Papillomavirus Infections/epidemiology, Papillomavirus Infections/virology, Prevalence, Risk Factors, Skin/virology, Smoking/epidemiology
Pubmed
Web of science
Create date
21/01/2013 15:02
Last modification date
20/08/2019 15:14
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