Simkania negevensis, an Example of the Diversity of the Antimicrobial Susceptibility Pattern among Chlamydiales.

Détails

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Etat: Public
Version: Final published version
ID Serval
serval:BIB_A96B1EBEB8DB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Simkania negevensis, an Example of the Diversity of the Antimicrobial Susceptibility Pattern among Chlamydiales.
Périodique
Antimicrobial agents and chemotherapy
Auteur(s)
Vouga M., Baud D., Greub G.
ISSN
1098-6596 (Electronic)
ISSN-L
0066-4804
Statut éditorial
Publié
Date de publication
08/2017
Peer-reviewed
Oui
Volume
61
Numéro
8
Pages
1-5
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Résumé
In past years, several <i>Chlamydia</i> -related bacteria have been discovered, including <i>Simkania negevensis</i> , the founding member of the <i>Simkaniaceae</i> family. We evaluated the antimicrobial susceptibility patterns of this emerging intracellular bacterium and highlighted significant differences, compared with related <i>Chlamydiales</i> members. <i>S. negevensis</i> was susceptible to macrolides, clindamycin, cyclines, rifampin, and quinolones. Importantly, unlike other <i>Chlamydiales</i> members, treatment with β-lactams and vancomycin did not induce the formation of aberrant bodies, leading to a completely resistant phenotype.

Mots-clé
Animals, Anti-Bacterial Agents/pharmacology, Cell Line, Cercopithecus aethiops, Chlamydiaceae Infections, Chlamydiales/drug effects, Clindamycin/pharmacology, Macrolides/pharmacology, Microbial Sensitivity Tests, Quinolones/pharmacology, Rifampin/pharmacology, Vancomycin/pharmacology, Vero Cells, beta-Lactams/pharmacology, Chlamydiales, Simkaniaceae, intracellular bacteria
Pubmed
Web of science
Open Access
Oui
Création de la notice
06/06/2017 17:16
Dernière modification de la notice
20/08/2019 15:13
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