Traitement differencie de l'oedeme maculaire cystoide inflammatoire postoperatoire et secondaire aux uveites. [Differential treatment of postoperative and uveitis-induced inflammatory cystoid macular edema]

Détails

ID Serval
serval:BIB_A946A122EAE1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Traitement differencie de l'oedeme maculaire cystoide inflammatoire postoperatoire et secondaire aux uveites. [Differential treatment of postoperative and uveitis-induced inflammatory cystoid macular edema]
Périodique
Klinische Monatsblatter fur Augenheilkunde
Auteur(s)
Guex-Crosier  Y., Othenin-Girard  P., Herbort  C. P.
ISSN
0023-2165 (Print)
Statut éditorial
Publié
Date de publication
05/1992
Volume
200
Numéro
5
Pages
367-73
Notes
Clinical Trial
Comparative Study
English Abstract
Journal Article --- Old month value: May
Résumé
Twenty-five eyes (23 patients) with inflammatory cystoid macular edema (CME) (11 after cataract surgery and 14 eyes (12 patients) with uveitis) were followed in a prospective open study. The aim was to determine the efficiency of a combined treatment of Diamox (acetazolamide), Voltaren Ophtha (diclofenac, a NSAID) and Ultracortenol (prednisolone acetate) and in the case of treatment failure, the usefulness of posterior subtenon's injections of corticosteroids (Kenacort 40 mg (triamcinolone)). Seven eyes (all pseudophakic CMEs) responded successfully to the initial therapy. Their mean visual acuity improved from 0.31 +/- 0.13 to 0.93 +/- 0.08 after 18 +/- 5 days (p less than or equal to 0.001). Of the sixteen of 18 evaluable eyes that were additionally treated with a mean of 3.28 +/- 1.07 three-weekly posterior subtenon's injections, 15 eyes including all uveitis CME responded to treatment. Their mean visual acuity improved from 0.49 +/- 0.20 to 0.96 +/- 0.31 (p less than or equal to 0.001). Two patients were excluded; in 22/23 eyes the sequential treatment was successful with an overall success rate of 95% of cases (improvement of five lines on the Snellen chart or final visual acuity of 0.8 or better). Initial angiographic cystoid macular edema was comparable and significantly improved after therapy in the two treatment groups. No mean intraocular pressure rise was noted after steroid injections. Measurement of anterior chamber inflammation with the laser flare-cell meter (Kowa FC-1000) showed elevated flare in all cases which significantly decreased in both treatment groups and represented a good follow-up parameter for the effect of antiinflammatory treatment and restoration of blood-ocular barrier.(ABSTRACT TRUNCATED AT 250 WORDS)
Mots-clé
Acetazolamide/*administration & dosage Adult Aged Aged, 80 and over Diclofenac/*administration & dosage Female Humans Injections *Lenses, Intraocular Macular Edema, Cystoid/*drug therapy Male Middle Aged Ophthalmic Solutions Postoperative Complications/*drug therapy Prednisolone/administration & dosage/*analogs & derivatives Prospective Studies Triamcinolone Acetonide/administration & dosage Uveitis/*complications/drug therapy Visual Acuity/drug effects
Pubmed
Web of science
Création de la notice
28/01/2008 13:45
Dernière modification de la notice
20/08/2019 16:13
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