Article: article from journal or magazin.
Simultaneous screening and quantification of several nonopiate narcotic analgesics and phencyclidine in human plasma using capillary gas chromatography.
Methods and Findings In Experimental and Clinical Pharmacology
This paper describes a procedure for the quantitative determination of alfentanil, dextromoramide, fentanyl, methadone, pentazocine, pethidine, phenoperidine and phencyclidine in human plasma. Some drug metabolites were included in the study. The procedure involves a simple alkaline extraction technique and capillary gas chromatography separation followed by a nitrogen-selective detection. Concentrations as low as 10 micrograms/l can be routinely evaluated, making this method suitable for use in overdose drug screening, therapeutic drug monitoring and pharmacokinetic studies.
Analgesics, Opioid/blood, Chromatography, Gas, Chromatography, High Pressure Liquid, Humans, Phencyclidine/blood
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