Stress ulcer prophylaxis in non-critically ill patients: a prospective evaluation of current practice in a general surgery department
Details
Serval ID
serval:BIB_A89DAFAF7479
Type
Inproceedings: an article in a conference proceedings.
Collection
Publications
Institution
Title
Stress ulcer prophylaxis in non-critically ill patients: a prospective evaluation of current practice in a general surgery department
Title of the conference
98th Annual Congress of the Swiss Society of Surgery
Address
Geneva, Switzerland, May 25-27, 2011
ISBN
0007-1323
Publication state
Published
Issued date
2011
Peer-reviewed
Oui
Volume
98
Series
British Journal of Surgery
Pages
7
Language
english
Notes
Publication type : Meeting Abstract
Abstract
Objective: There is little evidence regarding the benefit of stress ulcer prophylaxis (SUP) outside critical care setting. Over-prescription of SUP is not devoid of risks. This prospective study aimed to evaluate the use of proton pump inhibitors (PPIs) for SUP in a general surgery department.Methods: Data collection was performed prospectively during an 8-week period on patients hospitalized in a general surgery department (58 beds) by pharmacists. Patients with a PPI prescription for the treatment of ulcers, gastro-oesophageal reflux disease, oesophagitis or epigastric pain were excluded. Patients admitted twice during the study period were not re-included. The American Society of Health-System Pharmacists guidelines on SUP were used to assess the appropriateness of de novo PPI prescriptions.Results: Among 255 consecutive patients in the study, 138 (54%) received a prophylaxis with PPI, of which 86 (62%) were de novo PPI prescriptions. One-hundred twenty-nine patients (94%) received esomeprazole (according to the hospital drug policy). The most frequent dosage was 40 mg/day. Use of PPI for SUP was evaluated in 67 patients. Fifty-three patients (79%) had no risk factors for SUP. Twelve and 2 patients had one or two risk factors, respectively. At discharge, PPI prophylaxis was continued in 34% of patients with a de novo PPI prescription.Conclusion: This study highlights the overuse of PPIs in non-ICU patients and the inappropriate continuation of PPI prescriptions at discharge.Treatment
Keywords
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Web of science
Create date
30/05/2011 9:25
Last modification date
20/08/2019 15:13