Is it better to reduce the intervals between pulsed dye laser treatments for port wine stains in children? Laser Doppler Imaging based study.
Details
Serval ID
serval:BIB_A7C6C7D57062
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Is it better to reduce the intervals between pulsed dye laser treatments for port wine stains in children? Laser Doppler Imaging based study.
Journal
Journal of pediatric surgery
ISSN
1531-5037 (Electronic)
ISSN-L
0022-3468
Publication state
Published
Issued date
11/2020
Peer-reviewed
Oui
Volume
55
Number
11
Pages
2459-2465
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
Pulsed Dye Laser (PDL) is the treatment of choice of Port Wine Stains (PWS). Laser Doppler Imaging (LDI) has been used to evaluate the effectiveness of this treatment. In a previous study, we demonstrated that LDI allows an objective evaluation. The purpose of this study is to investigate if reducing the delay between two laser sessions could improve the clinical outcome.
This prospective study was conducted from September 2015 to November 2017. Three Laser sessions were performed every month in twenty patients with PWS. The PWS response was assessed by LDI after each session and at the end of the third one. The present study was compared to the first one.
The LDI confirmed the efficacy of PDL treatment with an average blanching rate of 26.7 %. The response is statistically significant after each session. When we compare both studies, there is an average decrease in vascularization of 0.42 for the first study and 0.50 for the present one.
This study allows us to validate the use of LDI for the numerical evaluation of PDL effect on PWS in children. However, we cannot confirm that reducing the interval between laser sessions could improve therapeutic outcomes.
Treatment Study Level II (Prospective Comparative Study).
This prospective study was conducted from September 2015 to November 2017. Three Laser sessions were performed every month in twenty patients with PWS. The PWS response was assessed by LDI after each session and at the end of the third one. The present study was compared to the first one.
The LDI confirmed the efficacy of PDL treatment with an average blanching rate of 26.7 %. The response is statistically significant after each session. When we compare both studies, there is an average decrease in vascularization of 0.42 for the first study and 0.50 for the present one.
This study allows us to validate the use of LDI for the numerical evaluation of PDL effect on PWS in children. However, we cannot confirm that reducing the interval between laser sessions could improve therapeutic outcomes.
Treatment Study Level II (Prospective Comparative Study).
Keywords
Pediatrics, Perinatology, and Child Health, Surgery, General Medicine, Angioma, Capillary malformation, Laser, Laser Doppler Imaging, Port wine stains
Pubmed
Web of science
Create date
23/01/2020 16:41
Last modification date
21/01/2021 7:25
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