The needle length of bacterial injectisomes is determined by a molecular ruler
Details
Serval ID
serval:BIB_A6C6BEB8BAD1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The needle length of bacterial injectisomes is determined by a molecular ruler
Journal
Science
ISSN
1095-9203 (Electronic)
ISSN-L
0036-8075
Publication state
Published
Issued date
2003
Volume
302
Number
5651
Pages
1757-60
Language
english
Notes
Journet, Laure
Agrain, Celine
Broz, Petr
Cornelis, Guy R
eng
Research Support, Non-U.S. Gov't
Science. 2003 Dec 5;302(5651):1757-60.
Agrain, Celine
Broz, Petr
Cornelis, Guy R
eng
Research Support, Non-U.S. Gov't
Science. 2003 Dec 5;302(5651):1757-60.
Abstract
Size determination represents a fundamental requirement for multicomponent biological structures. Some pathogenic bacteria possess a weapon derived from the flagellum. Like the flagellum, this type-III secretion apparatus, called the injectisome, has a transmembrane basal body, but the external component is a needle-like structure instead of a hook and a filament. Here, we provide evidence that the length of this needle is determined by the size of a protein, YscP, acting as a molecular ruler.
Keywords
Alleles, Bacterial Proteins/analysis/*chemistry/genetics/*physiology, Flagella/chemistry, Genes, Bacterial, Genetic Complementation Test, Microscopy, Electron, Mutation, Sequence Deletion, Yersinia enterocolitica/*chemistry/*ultrastructure
Pubmed
Create date
25/10/2017 10:05
Last modification date
20/08/2019 15:11