The needle length of bacterial injectisomes is determined by a molecular ruler

Détails

ID Serval
serval:BIB_A6C6BEB8BAD1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
The needle length of bacterial injectisomes is determined by a molecular ruler
Périodique
Science
Auteur(s)
Journet L., Agrain C., Broz P., Cornelis G. R.
ISSN
1095-9203 (Electronic)
ISSN-L
0036-8075
Statut éditorial
Publié
Date de publication
2003
Volume
302
Numéro
5651
Pages
1757-60
Langue
anglais
Notes
Journet, Laure
Agrain, Celine
Broz, Petr
Cornelis, Guy R
eng
Research Support, Non-U.S. Gov't
Science. 2003 Dec 5;302(5651):1757-60.
Résumé
Size determination represents a fundamental requirement for multicomponent biological structures. Some pathogenic bacteria possess a weapon derived from the flagellum. Like the flagellum, this type-III secretion apparatus, called the injectisome, has a transmembrane basal body, but the external component is a needle-like structure instead of a hook and a filament. Here, we provide evidence that the length of this needle is determined by the size of a protein, YscP, acting as a molecular ruler.
Mots-clé
Alleles, Bacterial Proteins/analysis/*chemistry/genetics/*physiology, Flagella/chemistry, Genes, Bacterial, Genetic Complementation Test, Microscopy, Electron, Mutation, Sequence Deletion, Yersinia enterocolitica/*chemistry/*ultrastructure
Pubmed
Création de la notice
25/10/2017 11:05
Dernière modification de la notice
20/08/2019 16:11
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