Place de la radiothérapie stéréotaxique dans le cancer du poumon non à petites cellules en oligoprogression [Place of stereotactic radiotherapy in oligoprogressive non-small cell lung cancer]
Details
State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_A69739694680
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Place de la radiothérapie stéréotaxique dans le cancer du poumon non à petites cellules en oligoprogression [Place of stereotactic radiotherapy in oligoprogressive non-small cell lung cancer]
Journal
Revue medicale suisse
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
01/06/2022
Peer-reviewed
Oui
Volume
18
Number
784
Pages
1125-1133
Language
french
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
This review of the literature provides an overview of the combination of stereotactic radiotherapy (SBRT) with immune checkpoint inhibitors (ICI) and tyrosine kinase inhibitors (TKI) in oligo-progressive non-small cell lung neoplasia. This combination showed local control of 76-100% and distant response rates of 8-60%. They reported progression-free survival of 2.7-24 months and overall survival of 13.4-41.2 months. All-grade toxicity rates ranged from 0% to 42%, with grade≥3 toxicity ranging from 0% to 14%. The combination of SBRT with ICI or TKIs exhibits a safe profile with high rates of local control with this combination. This could delay the use of a new line of systemic therapy in these patients with often limited therapeutic resources.
Keywords
Carcinoma, Non-Small-Cell Lung/radiotherapy, Humans, Lung, Lung Neoplasms/drug therapy, Lung Neoplasms/radiotherapy, Radiosurgery
Pubmed
Create date
07/08/2023 16:42
Last modification date
28/10/2023 7:21
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