Sentinel lymph node biopsy in nonmelanoma skin cancer patients.

Détails

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Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_A629C8976B94
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Sentinel lymph node biopsy in nonmelanoma skin cancer patients.
Périodique
Journal of Skin Cancer
Auteur(s)
Matthey-Giè M.L., Boubaker A., Letovanec I., Demartines N., Matter M.
ISSN
2090-2905 (Print)
ISSN-L
2090-2913
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
2013
Pages
267474
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
The management of lymph nodes in nonmelanoma skin cancer patients is currently still debated. Merkel cell carcinoma (MCC), squamous cell carcinoma (SCC), pigmented epithelioid melanocytoma (PEM), and other rare skin neoplasms have a well-known risk to spread to regional lymph nodes. The use of sentinel lymph node biopsy (SLNB) could be a promising procedure to assess this risk in clinically N0 patients. Metastatic SNs have been observed in 4.5-28% SCC (according to risk factors), in 9-42% MCC, and in 14-57% PEM. We observed overall 30.8% positive SNs in 13 consecutive patients operated for high-risk nonmelanoma skin cancer between 2002 and 2011 in our institution. These high rates support recommendation to implement SLNB for nonmelanoma skin cancer especially for SCC patients. Completion lymph node dissection following positive SNs is also a matter of discussion especially in PEM. It must be remembered that a definitive survival benefit of SLNB in melanoma patients has not been proven yet. However, because of its low morbidity when compared to empiric elective lymph node dissection or radiation therapy of lymphatic basins, SLNB has allowed sparing a lot of morbidity and could therefore be used in nonmelanoma skin cancer patients, even though a significant impact on survival has not been demonstrated.
Pubmed
Open Access
Oui
Création de la notice
16/04/2013 15:34
Dernière modification de la notice
20/08/2019 16:11
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