Clinical equivalence assessment of T2 synthesized pediatric brain magnetic resonance imaging.

Détails

ID Serval
serval:BIB_A60BED82B53C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Clinical equivalence assessment of T2 synthesized pediatric brain magnetic resonance imaging.
Périodique
Journal of neuroradiology = Journal de neuroradiologie
Auteur(s)
Kerleroux B., Kober T., Hilbert T., Serru M., Philippe J., Sirinelli D., Morel B.
ISSN
0150-9861 (Print)
ISSN-L
0150-9861
Statut éditorial
Publié
Date de publication
03/2019
Peer-reviewed
Oui
Volume
46
Numéro
2
Pages
130-135
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Automated synthetic magnetic resonance imaging (MRI) provides qualitative, weighted image contrasts as well as quantitative information from one scan and is well-suited for various applications such as analysis of white matter disorders. However, the synthesized contrasts have been poorly evaluated in pediatric applications. The purpose of this study was to compare the image quality of synthetic T2 to conventional turbo spin-echo (TSE) T2 in pediatric brain MRI.
This was a mono-center prospective study. Synthetic and conventional MRI acquisitions at 1.5 Tesla were performed for each patient during the same session using a prototype accelerated T2 mapping sequence package (TA <sub>synthetic</sub> =3:07min, TA <sub>conventional</sub> =2:33min). Image sets were blindly and randomly analyzed by pediatric neuroradiologists. Global image quality, morphologic legibility of standard structures and artifacts were assessed using a 4-point Likert scale. Inter-observer kappa agreements were calculated. The capability of the synthesized contrasts and conventional TSE T2 to discern normal and pathologic cases was evaluated.
Sixty patients were included. The overall diagnostic quality of the synthesized contrasts was non-inferior to conventional imaging scale (P=0.06). There was no significant difference in the legibility of normal and pathological anatomic structures of synthetized and conventional TSE T2 (all P>0.05) as well as for artifacts except for phase encoding (P=0.008). Inter-observer agreement was good to almost perfect (kappa between 0.66 and 1).
T2 synthesized contrasts, which also provides quantitative T2 information that could be useful, could be suggested as an equivalent technique in pediatric neuro-imaging, compared to conventional TSE T2.
Mots-clé
Adolescent, Artifacts, Brain Diseases/diagnostic imaging, Case-Control Studies, Child, Child, Preschool, Female, Humans, Image Enhancement/methods, Image Interpretation, Computer-Assisted/methods, Infant, Magnetic Resonance Imaging/methods, Male, Prospective Studies, Reproducibility of Results, Sensitivity and Specificity, Pediatric radiology, Quantitative imaging, Simulated contrast, Synthesized brain MRI
Pubmed
Web of science
Création de la notice
12/05/2018 10:08
Dernière modification de la notice
20/08/2019 16:11
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