Thrombolyse intracoronarienne comme traitement de l'infarctus en constitution [Intracoronary thrombolysis as a treatment for evolving myocardial infarction].

Details

Serval ID
serval:BIB_A46A4CB4EE68
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Thrombolyse intracoronarienne comme traitement de l'infarctus en constitution [Intracoronary thrombolysis as a treatment for evolving myocardial infarction].
Journal
Schweizerische Medizinische Wochenschrift
Author(s)
Sigwart U., Grbic M., Goy J.J., Grec V., Essinger A., Fischer A., Jaeger M., Morin D., Perret C., Sadeghi H.
ISSN
0036-7672 (Print)
ISSN-L
0036-7672
Publication state
Published
Issued date
1983
Volume
113
Number
45
Pages
1666-1670
Language
french
Abstract
Myocardial infarction is almost always the consequence of a thrombotic obstruction of one or more coronary arteries. We report our experience with the first 24 cases of intracoronary thrombolysis for recanalization of obstructed coronary arteries. 19 cases were successful, 1 case was partially successful and in 4 instances no reopening was observed. The amount of streptokinase used was 206 000 +/- 107 000 units, and reperfusion was achieved after 37 +/- 27.5 minutes. Recanalization of the vessel was accompanied by cessation of precordial pain and partial or complete normalization of the electrocardiogram. In one case bypass surgery was necessary because of reocclusion. Left ventricular function improvement after thrombolysis was dependent on the time-lag between occlusion and recanalization. These observations confirm others' experience that intracoronary thrombolysis appears to have favorable effects in patients with evolving myocardial infarction.
Keywords
Coronary Disease/complications, Coronary Disease/enzymology, Female, Humans, Male, Myocardial Infarction/prevention & control, Perfusion, Streptokinase/administration & dosage, Streptokinase/therapeutic use
Pubmed
Web of science
Create date
03/09/2011 20:16
Last modification date
20/08/2019 15:09
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