Correlative studies in neuro-oncology trials: should they influence treatment?

Détails

ID Serval
serval:BIB_A45CE919025A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Correlative studies in neuro-oncology trials: should they influence treatment?
Périodique
Current Oncology Reports
Auteur(s)
Hegi M.E., Stupp R.
ISSN
1523-3790 (Print)
ISSN-L
1523-3790
Statut éditorial
Publié
Date de publication
2006
Peer-reviewed
Oui
Volume
8
Numéro
1
Pages
54-57
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Recent molecular correlative studies accompanying clinical trials in glioma have provided strong evidence for prognostic markers and predictive factors for treatment response. However, to what extent can these markers influence the limited choice of therapeutic options? Do we further validate the markers in the next trials or move on, incorporate the markers for patient selection or stratification, aim at improving the modestly effective treatments by adding new drugs, and develop alternative therapy strategies for patients selected for their bad predictor?
Mots-clé
Brain Neoplasms/genetics, Brain Neoplasms/metabolism, Clinical Trials as Topic/methods, Female, Glioma/genetics, Glioma/metabolism, Humans, Male, Prognosis, Tumor Markers, Biological/genetics, Tumor Markers, Biological/metabolism
Pubmed
Création de la notice
28/01/2008 9:39
Dernière modification de la notice
03/03/2018 20:13
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