Article: article from journal or magazin.
Pathogenèse de la dermatite atopique [Pathogenesis of atopic dermatitis]
Revue Médicale Suisse
Although atopic dermatitis (AD) is a very frequent disease in our society, it is still poorly understood. AD mainly results from a complex interaction between a cutaneous barrier dysfunction, a dysregulation of the immune system and environmental factors. Recent studies have highlighted new mutations in genes coding for skin proteins inducing AD. Furthermore, a new cytokine named TSLP was discovered. TSLP plays a major role in allergic inflammation and represents a big step further in the understanding of AD pathogenesis. However, there are still a lot of unknown factors in this disease, which are actually thouroughly investigated in numerous studies.
Cytokines/genetics, Dermatitis, Atopic/genetics, Dermatitis, Atopic/physiopathology, Humans, Intermediate Filament Proteins/genetics, Skin Physiological Processes
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