Assessing arterial blood flow and vessel area variations using real-time zonal phase-contrast MRI.

Détails

ID Serval
serval:BIB_A32044DD10DE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Assessing arterial blood flow and vessel area variations using real-time zonal phase-contrast MRI.
Périodique
Journal of Magnetic Resonance Imaging
Auteur(s)
Oelhafen M., Schwitter J., Kozerke S., Luechinger R., Boesiger P.
ISSN
1053-1807 (Print)
ISSN-L
1053-1807
Statut éditorial
Publié
Date de publication
2006
Volume
23
Numéro
3
Pages
422-429
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Validation Studies
Publication Status: ppublish
Résumé
PURPOSE: To measure peripheral artery function using a real-time phase-contrast (PC)-MRI sequence with tailored image-processing algorithms for flow computation.
MATERIALS AND METHODS: An approach to real-time flow measurements was developed based on two-dimensional spatially selective excitation pulses and consecutive tailored processing of the data to derive blood flow and vessel area variations. The data acquisition strategy allows for flow measurements at high spatial and temporal resolutions of 1 mm(2) and 50 msec, respectively. In postprocessing the vessel area is automatically extracted using correlation measures in conjunction with morphological image operators. By means of in vitro and in vivo validations, it is shown that the current methods provide accurate and reproducible measurements of flow and vessel area variations.
RESULTS: In vitro the comparison between the lumen area measured with the presented method and the values obtained by caliper gauge measurement showed a difference of 3.4% +/- 3.4% (mean +/- 2 SD). Similarly, the comparison between the stroke volumes determined with the presented method and by stopwatch and bucket measurements yielded a difference of 6.1% +/- 2.1%. In vivo the results from the real-time measurements for lumen area and stroke volume were compared with those from a gated PC-MRI technique with differences of 4.8% +/- 14% and 3.0% +/- 24.7%, respectively.
CONCLUSION: The presented method constitutes a reliable tool set for quantifying the variations of blood flow and lumen area in the superficial femoral artery during reactive hyperemia and for studying their correlation with cardiovascular risk factors.
Mots-clé
Algorithms, Blood Flow Velocity/physiology, Femoral Artery/physiology, Humans, Hyperemia/diagnosis, Image Processing, Computer-Assisted, Magnetic Resonance Imaging/methods, Reproducibility of Results
Pubmed
Web of science
Open Access
Oui
Création de la notice
07/09/2011 18:11
Dernière modification de la notice
20/08/2019 16:08
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