Post-operative Langzeitentwicklung nach Vitrektomie und Optikusneurotomie bei retinalem Zentralvenenverschluss [Long-Term Functional and Anatomical Outcome of Radial Optic Neurotomy for Central Retinal Vein Occlusion]
Details
Serval ID
serval:BIB_A2BD49E320BD
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Post-operative Langzeitentwicklung nach Vitrektomie und Optikusneurotomie bei retinalem Zentralvenenverschluss [Long-Term Functional and Anatomical Outcome of Radial Optic Neurotomy for Central Retinal Vein Occlusion]
Journal
Klinische Monatsblatter fur Augenheilkunde
ISSN
1439-3999 (Electronic)
ISSN-L
0023-2165
Publication state
Published
Issued date
04/2016
Peer-reviewed
Oui
Volume
233
Number
4
Pages
444-447
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
Without treatment, the natural history of central retinal vein occlusion (CRVO) can result in severe loss of vision.
This was a retrospective study of 10 eyes with CRVO treated with pars plana vitrectomy (PPV), combined with radial optic neurotomy. The patients completed a minimum of 5 years follow-up.
Median age at the time of surgery was 67 ± 14 years. Median follow-up was 79 ± 9 months. Ischaemic changes were present in 4 patients pre-operatively. Baseline median logMAR BCVA was 2.00 ± 0.76 and improved significantly to a median of 0.35 ± 0.54 (p < 0.0001, two tailed t test) at 5 years follow-up. The baseline median central macular thickness (CMT) was 645 ± 108 µm and improved significantly, to a median of 203 ± 72 µm (p < 0.0001, two tailed t test). One of the patients developed neovascular complications during the follow-up period.
Our results compare very favorably with the natural history of CRVO. All patients demonstrated a trend to improved visual acuity, while only one of the patients developed neovascular complications. These results provide information on the potential long-term effect of PPV in patients with CRVO and may help to reassess the place of the surgical management of CRVO in patients who do not respond to medical treatment.
This was a retrospective study of 10 eyes with CRVO treated with pars plana vitrectomy (PPV), combined with radial optic neurotomy. The patients completed a minimum of 5 years follow-up.
Median age at the time of surgery was 67 ± 14 years. Median follow-up was 79 ± 9 months. Ischaemic changes were present in 4 patients pre-operatively. Baseline median logMAR BCVA was 2.00 ± 0.76 and improved significantly to a median of 0.35 ± 0.54 (p < 0.0001, two tailed t test) at 5 years follow-up. The baseline median central macular thickness (CMT) was 645 ± 108 µm and improved significantly, to a median of 203 ± 72 µm (p < 0.0001, two tailed t test). One of the patients developed neovascular complications during the follow-up period.
Our results compare very favorably with the natural history of CRVO. All patients demonstrated a trend to improved visual acuity, while only one of the patients developed neovascular complications. These results provide information on the potential long-term effect of PPV in patients with CRVO and may help to reassess the place of the surgical management of CRVO in patients who do not respond to medical treatment.
Keywords
Aged, Aged, 80 and over, Decompression, Surgical/methods, Female, Humans, Longitudinal Studies, Male, Middle Aged, Neurosurgical Procedures/methods, Optic Nerve/surgery, Retinal Vein Occlusion/complications, Retinal Vein Occlusion/diagnosis, Retinal Vein Occlusion/surgery, Retrospective Studies, Treatment Outcome, Vision Disorders/etiology, Vision Disorders/prevention & control, Visual Acuity, Vitrectomy/methods
Pubmed
Web of science
Create date
10/05/2016 17:33
Last modification date
20/08/2019 15:08
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