Teaching methods in the health sciences are evolving with societal changes and the needs of new generations. Gamification in the field of medical education is a fast-growing theme. The use of games in medical training activities engages participants in problem-solving by amplifying their emotional experience and promotes adult learning. At Unisanté (Centre for Primary Care and Public Health of the University of Lausanne), the MedEscapeRoom, an escape game on the outpatient management of acute vertigo, has been developed as a new teaching tool in undergraduate medical education through an exploratory approach and continuous improvement cycles. This article describes the development and evaluation of this pioneering teaching tool.