Metabolic effects of mental stress during over- and underfeeding in healthy women

Details

Serval ID
serval:BIB_A1F1ADBA6341
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Metabolic effects of mental stress during over- and underfeeding in healthy women
Journal
Obesity Research
Author(s)
Seematter  G., Dirlewanger  M., Rey  V., Schneiter  P., Tappy  L.
ISSN
1071-7323 (Print)
Publication state
Published
Issued date
01/2002
Volume
10
Number
1
Pages
49-55
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jan
Abstract
OBJECTIVE: To assess the short-term consequences of carbohydrate or fat overfeeding or of food restriction on the metabolic effects of mental stress in healthy lean women. RESEARCH METHODS AND PROCEDURES: The effects of a sympathetic activation elicited by mental stress were evaluated in a group of healthy women after standardized isocaloric feeding (ISO) or after a 3-day overfeeding with 40% excess calories as either carbohydrate overfeeding (CHO OF) or fat overfeeding (FAT OF). Oxygen consumption rate (VO(2)) was measured as an index of energy expenditure, and subcutaneous glycerol concentrations were monitored with microdialysis. The same measurements were performed in another group of healthy women after ISO and after a 3-day period of underfeeding with a protein sparing modified fast (UF). RESULTS: In all conditions, mental stress significantly increased heart rate, blood pressure, plasma norepinephrine and epinephrine concentrations, and VO(2), and produced a nonsignificant increase in subcutaneous glycerol concentrations. CHO OF and FAT OF did not alter the effects of mental stress on VO(2) and subcutaneous glycerol concentrations. In contrast, UF increased basal VO(2) but significantly reduced its stimulation by mental stress. UF also enhanced the increase in subcutaneous glycerol concentrations during mental stress. DISCUSSION: UF reduces the stimulation of energy expenditure and enhances lipolysis during sympathetic activation. These adaptations may be involved in mobilization of endogenous fat while limiting weight loss. In contrast, short-term overfeeding fails to alter the sympathetic control of energy expenditure and lipolysis.
Keywords
Adult Diet, Protein-Restricted Diet, Reducing Dietary Carbohydrates/*administration & dosage Dietary Fats/*administration & dosage Dietary Proteins/administration & dosage Eating/physiology/*psychology Energy Metabolism/physiology Epinephrine/blood Female Glycerol/analysis Humans Norepinephrine/blood Oxygen Consumption Stress, Psychological/*metabolism Sympathetic Nervous System/*physiology
Pubmed
Web of science
Open Access
Yes
Create date
24/01/2008 13:36
Last modification date
20/08/2019 15:07
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