Selective Culture Medium for Screening of Fosfomycin Resistance in Enterobacterales.
Details
Serval ID
serval:BIB_A135ED490121
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Selective Culture Medium for Screening of Fosfomycin Resistance in Enterobacterales.
Journal
Journal of clinical microbiology
ISSN
1098-660X (Electronic)
ISSN-L
0095-1137
Publication state
Published
Issued date
19/01/2022
Peer-reviewed
Oui
Volume
60
Number
1
Pages
e0206321
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
A selective medium for screening fosfomycin (FOS)-resistant Enterobacterales was developed. Performances of this medium were first evaluated by using cultures of a collection of 84 enterobacterial clinical strains (42 FOS susceptible and 42 FOS resistant). The SuperFOS medium showed excellent sensitivity and specificity of detection (100%) in those conditions. Then, by testing spiked stool and spiked urine specimens, it revealed excellent performances, with lower limits of identification ranging from 10 <sup>1</sup> to 10 <sup>2</sup> CFU/ml. This screening medium allows easy and accurate detection of FOS-resistant isolates regardless of their resistance mechanisms.
Keywords
Anti-Bacterial Agents/pharmacology, Anti-Bacterial Agents/therapeutic use, Fosfomycin/pharmacology, Humans, Klebsiella pneumoniae, Microbial Sensitivity Tests, beta-Lactamases, Escherichia coli, fosfomycin, screening medium
Pubmed
Web of science
Create date
25/10/2021 9:06
Last modification date
14/11/2023 8:09