Colder is better during hypothermic circulatory arrest for acute type A aortic dissection.
Details
Serval ID
serval:BIB_A08EDCC408A9
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Colder is better during hypothermic circulatory arrest for acute type A aortic dissection.
Journal
Scandinavian cardiovascular journal
ISSN
1651-2006 (Electronic)
ISSN-L
1401-7431
Publication state
Published
Issued date
04/2013
Peer-reviewed
Oui
Volume
47
Number
2
Pages
121-128
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
To evaluate the influence, on early postoperative outcomes, of temperature during hypothermic circulatory arrest in emergent surgery for acute type A aortic dissection.
Hypothermic circulatory arrest (HCA) with antegrade cerebral perfusion was performed in 63 patients who underwent emergent surgery for acute type A aortic dissection between 2000 and 2009. Patients were retrospectively separated in two groups: ( 1 ) deep HCA, lowest nasopharyngeal temperature < 17 °C (n = 29; 46%) and ( 2 ) moderate HCA, lowest nasopharyngeal temperature ≥ 17 °C (n = 34; 54%).
Hospital mortality reached 27%. The nasopharyngeal temperature did not influence postoperative mortality or neurological outcome. Patients with deep HCA had significantly lower rate of infection (33% vs. 69%; p = 0.009) and shorter median intensive care unit length of stay (4 days ( 17 ) vs. 15.5 days ( 26 ) p = 0.017). Multiple regression analysis revealed that the lowest nasopharyngeal temperature was the only significant variable associated with intensive care unit length of stay (p = 0.005).
Patients suffering from acute type A aortic dissection might benefit from colder hypothermia during circulatory arrest.
Hypothermic circulatory arrest (HCA) with antegrade cerebral perfusion was performed in 63 patients who underwent emergent surgery for acute type A aortic dissection between 2000 and 2009. Patients were retrospectively separated in two groups: ( 1 ) deep HCA, lowest nasopharyngeal temperature < 17 °C (n = 29; 46%) and ( 2 ) moderate HCA, lowest nasopharyngeal temperature ≥ 17 °C (n = 34; 54%).
Hospital mortality reached 27%. The nasopharyngeal temperature did not influence postoperative mortality or neurological outcome. Patients with deep HCA had significantly lower rate of infection (33% vs. 69%; p = 0.009) and shorter median intensive care unit length of stay (4 days ( 17 ) vs. 15.5 days ( 26 ) p = 0.017). Multiple regression analysis revealed that the lowest nasopharyngeal temperature was the only significant variable associated with intensive care unit length of stay (p = 0.005).
Patients suffering from acute type A aortic dissection might benefit from colder hypothermia during circulatory arrest.
Keywords
Acute Disease, Aged, Aneurysm, Dissecting/etiology, Aneurysm, Dissecting/mortality, Aneurysm, Dissecting/surgery, Aortic Aneurysm, Thoracic/etiology, Aortic Aneurysm, Thoracic/mortality, Aortic Aneurysm, Thoracic/surgery, Circulatory Arrest, Deep Hypothermia Induced/methods, Female, Hospital Mortality, Humans, Length of Stay, Male, Middle Aged, Retrospective Studies, Treatment Outcome
Pubmed
Web of science
Create date
28/03/2019 18:14
Last modification date
20/08/2019 15:06
Usage data
