Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Amyloïdose rénale [Renal amyloidosis].
Revue Médicale Suisse
Publication types: Case Reports ; English Abstract ; Journal Article ; ReviewPublication Status: ppublish
Amyloidosis is defined as the extracellular deposition of proteins that have the capacity to form beta-pleated sheets and become insoluble. More than 17 types of amyloidosis have been described. Systemic light chain amyloid (AL) and AA amyloid (secondary to chronic inflammatory process) are by far the most frequent forms of amyloidosis. In these systemic forms, organs involved are the kidneys, the heart and the gastrointestinal tract in AL amyloidosis. The diagnostic can be established only by tissue biopsy. Treatment of primary amyloidosis (AL) aims at suppressing the responsible clone whereas treatment of secondary amyloidosis relies on controlling the underlying inflammatory process. Prognosis is globally poor and depends on the extend of organs involvement particularly cardiac and renal. The prognosis is even worse in patients requiring dialysis.
Aged, Amyloidosis/diagnosis, Amyloidosis/epidemiology, Disease Progression, Humans, Incidence, Kidney Diseases/diagnosis, Kidney Diseases/epidemiology, Male, Prognosis, Renal Insufficiency, Chronic/diagnosis, Renal Insufficiency, Chronic/etiology
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