This work proposes a formalized model, grounded in forensic science, to support a unified understanding of the Trace across scientific disciplines. The model is precisely defined in mathematical terms that reflect the dynamics of an offense as expressed in Locard’s Exchange principle. Specifically, this mathematical ap-proach represents the Trace as the modification of a Scene, subsequently perceptible, resulting from the Event under investigation. Examples are provided to illustrate how this conceptualization applies to for-ensic science, including DNA and digital evidence. Broader implications of this model are presented in the context of COVID-19, emphasizing the value of cohesive scientific study of the Trace. The aim of this work is to stimulate more formalized study of the Trace, both from tangible and abstract perspectives, and to strengthen forensic science as a whole.