Subcortical electrophysiological activity is detectable with high-density EEG source imaging.

Détails

ID Serval
serval:BIB_9F23DF4256C1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Subcortical electrophysiological activity is detectable with high-density EEG source imaging.
Périodique
Nature communications
Auteur(s)
Seeber M., Cantonas L.M., Hoevels M., Sesia T., Visser-Vandewalle V., Michel C.M.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Statut éditorial
Publié
Date de publication
14/02/2019
Peer-reviewed
Oui
Volume
10
Numéro
1
Pages
753
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Résumé
Subcortical neuronal activity is highly relevant for mediating communication in large-scale brain networks. While electroencephalographic (EEG) recordings provide appropriate temporal resolution and coverage to study whole brain dynamics, the feasibility to detect subcortical signals is a matter of debate. Here, we investigate if scalp EEG can detect and correctly localize signals recorded with intracranial electrodes placed in the centromedial thalamus, and in the nucleus accumbens. Externalization of deep brain stimulation (DBS) electrodes, placed in these regions, provides the unique opportunity to record subcortical activity simultaneously with high-density (256 channel) scalp EEG. In three patients during rest with eyes closed, we found significant correlation between alpha envelopes derived from intracranial and EEG source reconstructed signals. Highest correlation was found for source signals in close proximity to the actual recording sites, given by the DBS electrode locations. Therefore, we present direct evidence that scalp EEG indeed can sense subcortical signals.
Mots-clé
Brain/diagnostic imaging, Brain/physiology, Brain/physiopathology, Brain Mapping, Deep Brain Stimulation/methods, Electrodes, Electroencephalography/instrumentation, Electroencephalography/methods, Electrophysiological Phenomena, Humans, Intralaminar Thalamic Nuclei/diagnostic imaging, Intralaminar Thalamic Nuclei/physiology, Intralaminar Thalamic Nuclei/physiopathology, Magnetic Resonance Imaging, Nucleus Accumbens/diagnostic imaging, Nucleus Accumbens/physiology, Nucleus Accumbens/physiopathology, Obsessive-Compulsive Disorder/diagnostic imaging, Obsessive-Compulsive Disorder/physiopathology, Obsessive-Compulsive Disorder/therapy, Scalp/diagnostic imaging, Scalp/physiology, Scalp/physiopathology, Tomography, X-Ray Computed, Tourette Syndrome/diagnostic imaging, Tourette Syndrome/physiopathology, Tourette Syndrome/therapy
Pubmed
Web of science
Open Access
Oui
Création de la notice
31/03/2019 15:30
Dernière modification de la notice
20/08/2019 16:05
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