Early KPC-Producing Klebsiella pneumoniae Bacteremia among Intensive Care Unit Patients Non-Colonized upon Admission.

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Serval ID
serval:BIB_9EAC3EC3B4EC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Production externe
Title
Early KPC-Producing Klebsiella pneumoniae Bacteremia among Intensive Care Unit Patients Non-Colonized upon Admission.
Journal
Polish journal of microbiology
Author(s)
Papadimitriou-Olivgeris M., Fligou F., Spiliopoulou I., Bartzavali C., Dodou V., Vamvakopoulou S., Koutsileou K., Zotou A., Anastassiou E.D., Christofidou M., Marangos M.
ISSN
1733-1331 (Print)
ISSN-L
1733-1331
Publication state
Published
Issued date
06/07/2017
Peer-reviewed
Oui
Volume
66
Number
2
Pages
251-254
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Among 140 patients colonized by KPC-producing Klebsiella pneumoniae (KPC-Kp) between fourth and seventh day of Intensive Care Unit stay, 24 developed bacteraemia immediately after colonization. Colistin-resistance of the colonizing isolate was the factor significantly associated with early KPC-Kp bacteraemia (P < 0.001; OR 6.6, 95% CI 2.4-18.4), a worrisome finding since infections by colistin-resistant isolates is associated with increased mortality due to limited remaining therapeutic options.
Keywords
Anti-Bacterial Agents, Bacteremia/diagnosis, Bacteremia/microbiology, Bacterial Proteins, Humans, Intensive Care Units, Klebsiella Infections/diagnosis, Klebsiella pneumoniae/isolation & purification, Patient Admission, Risk Factors, beta-Lactamases
DOI
10.5604/01.3001.0010.7863
Pubmed
28735313
Web of science
000405058700011
Open Access
Yes
Create date
20/12/2022 10:10
Last modification date
21/12/2022 6:53
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