Absence of residual Hodgkin's disease demonstrated by PET/CT in a deceased organ donor.

Détails

ID Serval
serval:BIB_9C57AF25D17D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Absence of residual Hodgkin's disease demonstrated by PET/CT in a deceased organ donor.
Périodique
Transplant international
Auteur(s)
Prior J.O., Duchosal M.A., Schmidt S., Turini P., Pilon N., Chioléro R., Pascual M.
ISSN
1432-2277 (Electronic)
ISSN-L
0934-0874
Statut éditorial
Publié
Date de publication
01/2010
Peer-reviewed
Oui
Volume
23
Numéro
1
Pages
101-104
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
With the current limited availability of organs for transplantation, it is important to consider marginal donor candidates, including survivors of potentially curable malignancies such as lymphoma. The absence of refractory/recurrent residual disease at the time of brain death can be difficult to establish. Therefore, it is critical to have objective data to decide whether to proceed or not with organ procurement and transplantation. We report a unique situation in which (18)F-fluorodeoxyglucose positron emission tomography (PET) was used to rule out Hodgkin's lymphoma recurrence in a 33-year-old, heart-beating, brain-dead, potential donor with a past history of Hodgkin's disease and a persistent mediastinal mass. PET showed no significant uptake in the mass, allowing organ donation and transplantation to occur. We present a new means of evaluating potential brain-dead donors with a past history of some lymphoma, whereby PET may help transplant physicians by optimizing donation safety while rationalizing the inclusion of marginal donors.

Mots-clé
Adult, Brain Death/pathology, Female, Fluorodeoxyglucose F18, Hodgkin Disease/pathology, Humans, Neoplasm, Residual/pathology, Positron-Emission Tomography, Radiopharmaceuticals, Tissue Donors, Tissue and Organ Procurement/methods, Tissue and Organ Procurement/standards, Tomography, X-Ray Computed
Pubmed
Web of science
Open Access
Oui
Création de la notice
15/12/2009 14:00
Dernière modification de la notice
20/08/2019 15:03
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