Syndrome sérotoninergique: mise au point et revue des cas annoncés en Suisse [Serotonin syndrome: review and case series from the Swiss pharmacovigilance system].

Details

Serval ID
serval:BIB_9A9E62270B8A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Syndrome sérotoninergique: mise au point et revue des cas annoncés en Suisse [Serotonin syndrome: review and case series from the Swiss pharmacovigilance system].
Journal
Revue Médicale Suisse
Author(s)
Chassot M., Munz T., Livio F., Buclin T.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2012
Volume
8
Number
360
Pages
2086-2090
Language
french
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Abstract
Serotonin syndrome is a potential adverse reaction to drugs increasing serotoninergic activity in the nervous system, some of them being frequently prescribed, such as antidepressant drugs. As clinical presentation is variable and often aspecific, diagnosing serotonin syndrome can be a challenge, particularly in mild cases. Serious forms can be lethal. The aim of this article is to increase practitioners awareness of this syndrome by reviewing current knowledge on physiopathology, clinical presentation and therapy. We also analyzed the 102 cases notified to Swissmedic from 1998 to 2009, focusing on patients profile and suspected drugs.
Keywords
Diagnosis, Differential, Humans, Pharmacovigilance, Serotonin Syndrome/diagnosis, Serotonin Syndrome/epidemiology, Switzerland
Pubmed
Create date
15/02/2013 12:01
Last modification date
23/08/2019 6:26
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