TREXMO: a translation tool to support the use of regulatory occupational exposure models

Détails

Ressource 1Télécharger: BIB_9A174C15E91B.P001.pdf (494.17 [Ko])
Etat: Serval
Version: Author's accepted manuscript
ID Serval
serval:BIB_9A174C15E91B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
TREXMO: a translation tool to support the use of regulatory occupational exposure models
Périodique
Annals of Occupational Hygiene
Auteur(s)
Savic Nenad, Racordon Dimitri, Buchs Didier, Gasic Bojan, Vernez Dernez
ISSN
1475-3162 (Electronic)
ISSN-L
0003-4878
Statut éditorial
Publié
Date de publication
10/2016
Peer-reviewed
Oui
Volume
60
Numéro
8
Pages
991-1008
Langue
anglais
Résumé
Occupational exposure models vary significantly in their complexity, purpose, and the level of expertise required from the user. Different parameters in the same model may lead to different exposure estimates for the same exposure situation. This paper presents a tool developed to deal with this concern-TREXMO or TRanslation of EXposure MOdels. TREXMO integrates six commonly used occupational exposure models, namely, ART v.1.5, STOFFENMANAGER(®) v.5.1, ECETOC TRA v.3, MEASE v.1.02.01, EMKG-EXPO-TOOL, and EASE v.2.0. By enabling a semi-automatic translation between the parameters of these six models, TREXMO facilitates their simultaneous use. For a given exposure situation, defined by a set of parameters in one of the models, TREXMO provides the user with the most appropriate parameters to use in the other exposure models. Results showed that, once an exposure situation and parameters were set in ART, TREXMO reduced the number of possible outcomes in the other models by 1-4 orders of magnitude. The tool should manage to reduce the uncertain entry or selection of parameters in the six models, improve between-user reliability, and reduce the time required for running several models for a given exposure situation. In addition to these advantages, registrants of chemicals and authorities should benefit from more reliable exposure estimates for the risk characterization of dangerous chemicals under Regulation, Evaluation, Authorisation and restriction of CHemicals (REACH).
Mots-clé
Occupational Exposure, Models, Theoretical
Pubmed
Web of science
Open Access
Oui
Création de la notice
07/07/2016 14:53
Dernière modification de la notice
08/05/2019 22:33
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