Influence of perinatal, developmental and environmental factors on cognitive abilities of preterm children without major impairments at 5 years.

Details

Serval ID
serval:BIB_99C06A3D7001
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Influence of perinatal, developmental and environmental factors on cognitive abilities of preterm children without major impairments at 5 years.
Journal
Early Human Development
Author(s)
Fawer C.L., Besnier S., Forcada M., Buclin T., Calame A.
ISSN
0378-3782 (Print)
ISSN-L
0378-3782
Publication state
Published
Issued date
1995
Volume
43
Number
2
Pages
151-164
Language
english
Notes
Publication types: Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
Publication Status: ppublish
Abstract
The relative role of perinatal factors (birthweight, gestational age, gender, asphyxia, mechanical ventilation and cerebral lesions), developmental factors (neuromotor development during the first 18 months of life) and environmental factors (socio-economic status and bilingualism) on cognitive abilities was evaluated in a cohort of preterm children who had been prospectively examined for haemorrhage (PVH) and periventricular leucomalacia (PVL) and followed-up to 5 years of age. Standardized neurological examinations and development assessment including tests of cognitive function were carried out. Major impairments could be ascribed to the presence of large PVL changes. Among the 226 children without major impairment, the overall incidence of neuropsychological anomalies (neuromotor, language, visual, auditory and behaviour anomalies) was 46.5% and did not differ within ultrasound groups (normal scans, PVH and small PVL). However, children with small changes of PVL presented more abnormal neuromotor development within the first 18 months of life and had more complex neuropsychological anomalies at 5 years. The multiple regression analysis (General Intellectual Index (GII) predicted = 113.7 - coefficient x social class - 8.5 x bilingualism - 5.5 x dystonia + 1.4 x gestational age + 8 x mechanical ventilation) showed that socioeconomic status was the most important factor affecting the General Intellectual Index (GII). The contribution of sex and cerebral lesions was not significant. As children grew-up, environmental factors seemed to overcome perinatal factors.
Keywords
Asphyxia Neonatorum/complications, Birth Weight, Cerebral Hemorrhage/complications, Cerebral Hemorrhage/ultrasonography, Child Development, Cognition, Environment, Female, Follow-Up Studies, Gestational Age, Humans, Infant, Newborn, Infant, Premature, Language, Leukomalacia, Periventricular/complications, Leukomalacia, Periventricular/ultrasonography, Male, Respiration, Artificial, Sex Characteristics, Social Class
Pubmed
Web of science
Create date
21/01/2008 11:15
Last modification date
20/08/2019 15:01
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