Ultraviolet radiation-induced histopathological changes in the skin of the marsupial Monodelphis domestica. I. The effects of acute and chronic exposures and of photoreactivation treatment
Details
Serval ID
serval:BIB_978070A4BD75
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Ultraviolet radiation-induced histopathological changes in the skin of the marsupial Monodelphis domestica. I. The effects of acute and chronic exposures and of photoreactivation treatment
Journal
British Journal of Dermatology
ISSN
0007-0963 (Print)
Publication state
Published
Issued date
1985
Volume
113
Number
2
Pages
219-227
Notes
DA - 19851017
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
RN - 0 (Pyrimidine Dimers)
SB - IM
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
RN - 0 (Pyrimidine Dimers)
SB - IM
Abstract
Post-ultraviolet radiation (UVR) treatment of the South American opossum, Monodelphis domestica with long-wavelength radiation (320-400 nm) suppressed the induction of histopathological alterations in the skin. This study identifies DNA as a primary chromophore involved in the induction of various photobiological responses of the skin such as hyperplasia and sunburn cell formation, and also identified pyrimidine dimers as one responsible DNA lesion. The histology of skin from opossums exposed to multiple doses of UVR showed that pre-malignant changes had occurred in the skin
Keywords
anatomy & histology/Animals/Dna/DNA Repair/etiology/Hyperplasia/Light/Neoplasms,Radiation-Induced/Opossums/pathology/physiology/Precancerous Conditions/Pyrimidine Dimers/Radiation Dosage/radiation effects/Skin/Skin Neoplasms/Sunburn/Time Factors/Ultraviolet Rays
Pubmed
Web of science
Create date
18/02/2008 18:33
Last modification date
20/08/2019 15:59
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