Reduced orbitofrontal cortical thickness in male adolescents with internet addiction.

Details

Serval ID
serval:BIB_9655FF3E7E27
Type
Article: article from journal or magazin.
Collection
Publications
Title
Reduced orbitofrontal cortical thickness in male adolescents with internet addiction.
Journal
Behavioral and brain functions
Author(s)
Hong S.B., Kim J.W., Choi E.J., Kim H.H., Suh J.E., Kim C.D., Klauser P., Whittle S., Yűcel M., Pantelis C., Yi S.H.
ISSN
1744-9081 (Electronic)
ISSN-L
1744-9081
Publication state
Published
Issued date
12/03/2013
Peer-reviewed
Oui
Volume
9
Pages
11
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Abstract
The orbitofrontal cortex (OFC) has consistently been implicated in the pathology of both drug and behavioral addictions. However, no study to date has examined OFC thickness in internet addiction. In the current study, we investigated the existence of differences in cortical thickness of the OFC in adolescents with internet addiction. On the basis of recently proposed theoretical models of addiction, we predicted a reduction of thickness in the OFC of internet addicted individuals.
Participants were 15 male adolescents diagnosed as having internet addiction and 15 male healthy comparison subjects. Brain magnetic resonance images were acquired on a 3T MRI and group differences in cortical thickness were analyzed using FreeSurfer. Our results confirmed that male adolescents with internet addiction have significantly decreased cortical thickness in the right lateral OFC (p<0.05).
This finding supports the view that the OFC alterations in adolescents with internet addiction reflect a shared neurobiological marker of addiction-related disorders in general.
Keywords
Adolescent, Behavior, Addictive/pathology, Case-Control Studies, Data Interpretation, Statistical, Humans, Image Processing, Computer-Assisted, Internet, Magnetic Resonance Imaging, Male, Prefrontal Cortex/pathology, Psychiatric Status Rating Scales, Video Games
Pubmed
Web of science
Open Access
Yes
Create date
07/02/2019 9:31
Last modification date
02/09/2019 5:26
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