Patterns of positive selection in seven ant genomes.

Détails

Ressource 1Télécharger: BIB_95722591AAD3.P001.pdf (1132.24 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_95722591AAD3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Patterns of positive selection in seven ant genomes.
Périodique
Molecular Biology and Evolution
Auteur(s)
Roux J., Privman E., Moretti S., Daub J.T., Robinson-Rechavi M., Keller L.
ISSN
1537-1719 (Electronic)
ISSN-L
0737-4038
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
31
Numéro
7
Pages
1661-1685
Langue
anglais
Résumé
The evolution of ants is marked by remarkable adaptations that allowed the development of very complex social systems. To identify how ant-specific adaptations are associated with patterns of molecular evolution, we searched for signs of positive selection on amino-acid changes in proteins. We identified 24 functional categories of genes which were enriched for positively selected genes in the ant lineage. We also reanalyzed genome-wide data sets in bees and flies with the same methodology to check whether positive selection was specific to ants or also present in other insects. Notably, genes implicated in immunity were enriched for positively selected genes in the three lineages, ruling out the hypothesis that the evolution of hygienic behaviors in social insects caused a major relaxation of selective pressure on immune genes. Our scan also indicated that genes implicated in neurogenesis and olfaction started to undergo increased positive selection before the evolution of sociality in Hymenoptera. Finally, the comparison between these three lineages allowed us to pinpoint molecular evolution patterns that were specific to the ant lineage. In particular, there was ant-specific recurrent positive selection on genes with mitochondrial functions, suggesting that mitochondrial activity was improved during the evolution of this lineage. This might have been an important step toward the evolution of extreme lifespan that is a hallmark of ants.
Mots-clé
Drosophila, Hymenoptera, aging, bees, comparative genomics, dN/dS, immunity, lifespan, metabolism, neurogenesis, olfactory receptors, sociality
Pubmed
Web of science
Open Access
Oui
Création de la notice
15/04/2014 16:18
Dernière modification de la notice
20/08/2019 14:57
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