A new method for quantitative ultrasound measurements at multiple skeletal sites: first results of precision and fracture discrimination.

Details

Serval ID
serval:BIB_952363CEF65D
Type
Article: article from journal or magazin.
Collection
Publications
Title
A new method for quantitative ultrasound measurements at multiple skeletal sites: first results of precision and fracture discrimination.
Journal
Journal of Clinical Densitometry
Author(s)
Barkmann R., Kantorovich E., Singal C., Hans D., Genant H.K., Heller M., Glüer C.C.
ISSN
1094-6950
Publication state
Published
Issued date
2000
Peer-reviewed
Oui
Volume
3
Number
1
Pages
1-7
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Abstract
We investigated a new multisite quantitative ultrasound device that measures the acoustic velocity in axial transmission mode along the cortex. Using a prototype of the Omnisense (Sunlight Ultrasound Technologies, Rehovot, Israel), we tested the performance of this instrument at four sites of the skeleton: radius, ulna, metacarpal, and phalanx. Intraobserver (interobserver) precision errors ranged from 0.2% to 0.3% (0.3% to 0.7%) for triplicate measurements with repositioning. Fracture discrimination was tested by comparing a group of 34 women who had previously suffered a fracture of the hip, spine, ankle, or forearm to a group of 28 healthy women who had not suffered a fracture. Age-adjusted standardized odds ratios ranged from 1.6 to 4.5. Except for the ulna the sites showed a significant fracture discrimination (p < 0.01). The areas under the receiver operating curves (ROC) curves were from 0.88 to 0.89 for radius, metacarpal, and phalanx. A combination of the results from the three sites showed a significant increase of the ROC area to 0.95 (p < 0. 05). Our results show promising performance of this new device. The ability to measure a large variety of sites and the potential to combine these measurements are promising with regard to optimizing fracture risk assessment.
Keywords
Aged, Bone and Bones, Evaluation Studies as Topic, Female, Fractures, Bone, Humans, Logistic Models, Observer Variation, Osteoporosis, Pilot Projects, ROC Curve, Ultrasonography
Pubmed
Web of science
Create date
02/03/2009 12:33
Last modification date
20/08/2019 14:57
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