Hirntumoren der Fossa posterior im Kindesalter. Eine Uebersicht der Patienten der Medizinischen Universitats-Kinderklinik Bern in den Jahren 1990 bis 1994. [Brain tumors of the posterior fossa in childhood. An overview of the patients of the medical university hospital's pediatric department Berne in the years 1990-1994]

Détails

ID Serval
serval:BIB_942D8132DA73
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Hirntumoren der Fossa posterior im Kindesalter. Eine Uebersicht der Patienten der Medizinischen Universitats-Kinderklinik Bern in den Jahren 1990 bis 1994. [Brain tumors of the posterior fossa in childhood. An overview of the patients of the medical university hospital's pediatric department Berne in the years 1990-1994]
Périodique
Schweizerische Rundschau fur Medizin Praxis
Auteur(s)
Mazzucco  A., von der Weid  N., Godoy  N.
ISSN
1013-2058 (Print)
Statut éditorial
Publié
Date de publication
08/1996
Volume
85
Numéro
34
Pages
1001-4
Notes
English Abstract
Journal Article --- Old month value: Aug 20
Résumé
During the time period 1990 to 1994 the mean incidence of pediatric brain tumors in Switzerland reached 2.78 new cases per 100,000 children under 16 years of age per year. In the same time period 33 children (18 male, 15 female) were newly diagnosed at the University Hospital of Berne with a tumor located in the posterior fossa. Ten (31%) had a medulloblastoma, nine (27%) an astrocytoma, six (18%) a brain-stem glioma, four (12%) an ependymoma, and four (12%) had other tumor types. Besides typical signs and symptoms of increased intracranial pressure, cranial nerve palsies or visual problems were frequently found (in 70% and 30% of the patients, resp.). The median time interval between the first symptoms and the definite diagnosis was four months. Central in the therapeutic approach remained the neurosurgical removal of the tumor, which was realized in 85% of the cases. As adjuvant weapons, radiotherapy and/or chemotherapy (in 45% and 48.5%, resp.) were used with curative aims. Globally 16 of the 31 evaluable children 51%) survived disease-free at the time of evaluation with a median survival of 42 months. The two-year survival rates were 83% for astrocytoma, 50% for ependymoma, 46.5% for medulloblastoma and 40% for brain-stem glioma. These observations emphasize the prognostic significance of histology in pediatric brain tumors.
Mots-clé
Adolescent Brain Neoplasms/diagnosis/*epidemiology/mortality/therapy Child Child, Preschool Combined Modality Therapy *Cranial Fossa, Posterior Female Humans Incidence Infant Infant, Newborn Male Survival Rate Switzerland/epidemiology
Pubmed
Création de la notice
25/01/2008 11:35
Dernière modification de la notice
03/03/2018 19:36
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