Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Complete and long-lasting regression of disseminated multiple skin melanoma metastases under treatment with cyclooxygenase-2 inhibitor.
Publication types: Case Reports ; Journal Article - Publication Status: ppublish
Experimental and clinical evidence indicates that non-steroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors may have anti-cancer activities. Here we report on a patient with a metastatic melanoma of the leg who experienced a complete and sustained regression of skin metastases upon continuous single treatment with the cyclooxygenase-2 inhibitor rofecoxib. Our observations indicate that the inhibition of cyclooxygenase-2 can lead to the regression of disseminated skin melanoma metastases, even after failure of chemotherapy.
Aged, Cyclooxygenase 2 Inhibitors, Female, Humans, Lactones, Melanoma, Remission Induction, Skin Neoplasms, Sulfones
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