Complete and long-lasting regression of disseminated multiple skin melanoma metastases under treatment with cyclooxygenase-2 inhibitor.

Détails

ID Serval
serval:BIB_942B1D56E92B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Complete and long-lasting regression of disseminated multiple skin melanoma metastases under treatment with cyclooxygenase-2 inhibitor.
Périodique
Melanoma research
Auteur(s)
Lejeune F.J., Monnier Y., Rüegg C.
ISSN
0960-8931
Statut éditorial
Publié
Date de publication
2006
Peer-reviewed
Oui
Volume
16
Numéro
3
Pages
263-5
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article - Publication Status: ppublish
Résumé
Experimental and clinical evidence indicates that non-steroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors may have anti-cancer activities. Here we report on a patient with a metastatic melanoma of the leg who experienced a complete and sustained regression of skin metastases upon continuous single treatment with the cyclooxygenase-2 inhibitor rofecoxib. Our observations indicate that the inhibition of cyclooxygenase-2 can lead to the regression of disseminated skin melanoma metastases, even after failure of chemotherapy.
Mots-clé
Aged, Cyclooxygenase 2 Inhibitors, Female, Humans, Lactones, Melanoma, Remission Induction, Skin Neoplasms, Sulfones
Pubmed
Web of science
Création de la notice
28/01/2008 9:36
Dernière modification de la notice
24/09/2018 11:48
Données d'usage