Chromatin insulators and Prospective Application for gene Therapy.

Détails

ID Serval
serval:BIB_9404481E95ED
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Chromatin insulators and Prospective Application for gene Therapy.
Périodique
Gene Therapy Review
Auteur(s)
Gaussin A., Mermod N.
ISSN
1792-0094 (print)
1792-0108 (online)
Statut éditorial
Publié
Date de publication
2009
Pages
on line
Langue
anglais
Résumé
Integrating viral vectors hold great promise as gene transfer vectors for gene therapy purposes because they allow maintaining long-term expression of the therapeutic transgene throughout cell divisions. However, many issues related to integration of the provirus remain as a substantial risk for patients. The use of chromatin insulators has been proposed as a possible solution to problems raised by the integration of the vector.
Création de la notice
04/01/2010 14:37
Dernière modification de la notice
20/08/2019 14:56
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