Article: article from journal or magazin.
Chromatin insulators and Prospective Application for gene Therapy.
Gene Therapy Review
1792-0094 [print];1792-0108 [online]
Integrating viral vectors hold great promise as gene transfer vectors for gene therapy purposes because they allow maintaining long-term expression of the therapeutic transgene throughout cell divisions. However, many issues related to integration of the provirus remain as a substantial risk for patients. The use of chromatin insulators has been proposed as a possible solution to problems raised by the integration of the vector.
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