Homocysteate and homocysteine sulfinate, excitatory transmitter candidates present in rat astroglial cultures.
Details
Serval ID
serval:BIB_940421FCB2D2
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Homocysteate and homocysteine sulfinate, excitatory transmitter candidates present in rat astroglial cultures.
Journal
Neuroscience Letters
ISSN
0304-3940 (Print)
ISSN-L
0304-3940
Publication state
Published
Issued date
1992
Peer-reviewed
Oui
Volume
145
Number
1
Pages
6-9
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
The presence of homocysteate and homocysteine sulfinate was demonstrated in extracts prepared from cultures of rat cortical and cerebellar astrocytes as well as from C6 glioblastoma cells by o-phthalaldehyde derivatization and subsequent HPLC analysis. Homocysteate-like immunoreactivity was found in cultured cortical astrocytes by postembedding immunocytochemistry at the level of light microscopy. These findings support the notion of a glial localization of the excitatory transmitter candidate homocysteate.
Keywords
Animals, Animals, Newborn/physiology, Astrocytes/chemistry, Astrocytes/metabolism, Bucladesine/metabolism, Chromatography, High Pressure Liquid, Female, Homocysteine/analogs & derivatives, Homocysteine/metabolism, Immunohistochemistry, Neuroglia/chemistry, Neuroglia/metabolism, Neurotransmitter Agents/metabolism, Pregnancy, Rats
Pubmed
Web of science
Create date
07/03/2014 12:23
Last modification date
20/08/2019 15:56