Evaluation of a clinical tool for early etiology identification in status epilepticus.

Détails

Ressource 1Télécharger: BIB_93D2D51B8589.P001.pdf (2852.99 [Ko])
Etat: Serval
Version: Author's accepted manuscript
ID Serval
serval:BIB_93D2D51B8589
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Evaluation of a clinical tool for early etiology identification in status epilepticus.
Périodique
Epilepsia
Auteur(s)
Alvarez V., Westover M.B., Drislane F.W., Dworetzky B.A., Curley D., Lee J.W., Rossetti A.O.
ISSN
1528-1167 (Electronic)
ISSN-L
0013-9580
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
55
Numéro
12
Pages
2059-2068
Langue
anglais
Notes
Publication types: Journal Article, psf : Full-Length Original Research
Résumé
OBJECTIVES: Because early etiologic identification is critical to select appropriate specific status epilepticus (SE) management, we aim to validate a clinical tool we developed that uses history and readily available investigations to guide prompt etiologic assessment.
METHODS: This prospective multicenter study included all adult patients treated for SE of all but anoxic causes from four academic centers. The proposed tool is designed as a checklist covering frequent precipitating factors for SE. The study team completed the checklist at the time the patient was identified by electroencephalography (EEG) request. Only information available in the emergency department or at the time of in-hospital SE identification was used. Concordance between the etiology indicated by the tool and the determined etiology at hospital discharge was analyzed, together with interrater agreement.
RESULTS: Two hundred twelve patients were included. Concordance between the etiology hypothesis generated using the tool and the finally determined etiology was 88.7% (95% confidence interval (CI) 86.4-89.8) (κ = 0.88). Interrater agreement was 83.3% (95% CI 80.4-96) (κ = 0.81).
SIGNIFICANCE: This tool is valid and reliable for identification early the etiology of an SE. Physicians managing patients in SE may benefit from using it to identify promptly the underlying etiology, thus facilitating selection of the appropriate treatment.
Pubmed
Web of science
Création de la notice
06/01/2015 11:43
Dernière modification de la notice
03/03/2018 19:35
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