Postmortem whole-body CT angiography: evaluation of two contrast media solutions.

Détails

ID Serval
serval:BIB_938799F9E53E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Postmortem whole-body CT angiography: evaluation of two contrast media solutions.
Périodique
Ajr. American Journal of Roentgenology
Auteur(s)
Ross S., Spendlove D., Bolliger S., Christe A., Oesterhelweg L., Grabherr S., Thali M.J., Gygax E.
ISSN
1546-3141[electronic], 0361-803X[linking]
Statut éditorial
Publié
Date de publication
2008
Volume
190
Numéro
5
Pages
1380-1389
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
OBJECTIVE: The objective of our study was to establish a standardized procedure for postmortem whole-body CT-based angiography with lipophilic and hydrophilic contrast media solutions and to compare the results of these two methods. MATERIALS AND METHODS: Minimally invasive postmortem CT angiography was performed on 10 human cadavers via access to the femoral blood vessels. Separate perfusion of the arterial and venous systems was established with a modified heart-lung machine using a mixture of an oily contrast medium and paraffin (five cases) and a mixture of a water-soluble contrast medium with polyethylene glycol (PEG) 200 in the other five cases. Imaging was executed with an MDCT scanner. RESULTS: The minimally invasive femoral approach to the vascular system provided a good depiction of lesions of the complete vascular system down to the level of the small supplying vessels. Because of the enhancement of well-vascularized tissues, angiography with the PEG-mixed contrast medium allowed the detection of tissue lesions and the depiction of vascular abnormalities such as pulmonary embolisms or ruptures of the vessel wall. CONCLUSION: The angiographic method with a water-soluble contrast medium and PEG as a contrast-agent dissolver showed a clearly superior quality due to the lack of extravasation through the gastrointestinal vascular bed and the enhancement of soft tissues (cerebral cortex, myocardium, and parenchymal abdominal organs). The diagnostic possibilities of these findings in cases of antemortem ischemia of these tissues are not yet fully understood.
Mots-clé
Adult, Aged, Aged, 80 and over, Angiography, Autopsy/methods, Cadaver, Contrast Media, Drug Carriers, Humans, Iodized Oil/diagnostic use, Middle Aged, Polyethylene Glycols, Tomography, X-Ray Computed, Triiodobenzoic Acids/diagnostic use
Pubmed
Web of science
Création de la notice
04/03/2011 17:33
Dernière modification de la notice
29/05/2018 10:58
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