Kinetic assisted venous drainage for orthotopic heart transplantation in patients under mechanical circulatory support: a double-edged sword.

Details

Serval ID
serval:BIB_92310E371AC9
Type
Article: article from journal or magazin.
Collection
Publications
Title
Kinetic assisted venous drainage for orthotopic heart transplantation in patients under mechanical circulatory support: a double-edged sword.
Journal
European journal of cardio-thoracic surgery
Author(s)
Kirsch M.E., Kostantinos Z., Ali F., Vermes E., Bajan G., Loisance D.Y.
ISSN
1010-7940 (Print)
ISSN-L
1010-7940
Publication state
Published
Issued date
03/2008
Peer-reviewed
Oui
Volume
33
Number
3
Pages
418-423
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Heart transplantation in patients supported with ventricular assist devices (VADs) entails a high risk of injury at resternotomy. Prior femorofemoral bypass is the preferred approach in these patients, but poor venous drainage may restrict arterial flow rate.
We compared bypass parameters, transfusion requirements and postoperative outcome in 33 consecutive patients (40.4+/-12.2 years old, 28 men) assisted with the Thoratec paracorporeal VAD (mean duration, 3.0+/-2.96 months) undergoing transplantation using either gravity siphon drainage (GSD, n=16) or kinetic assisted venous drainage (KAVD, n=17).
Cannulation technique, perfusion pressure, temperature and duration were similar between groups. There were no significant differences in arterial re-infusion flow rates (GSD, 3.6+/-0.7 vs KAVD, 3.8+/-0.6l/min, p=0.5). KAVD patients had a lower mean S(v)O(2) and a higher desaturation index than GSD patients (69.5+/-4.6 vs 76.1+/-5.4mmHg, p=0.004; and 0.63+/-0.23 vs 0.25+/-0.63, p=0.0001, respectively). Perioperative requirements in fresh frozen plasma and platelet transfusions were significantly higher in KAVD patients. However, there were no differences in postoperative patient outcome.
Perceived benefits on venous return associated with KAVD do not necessarily translate into improved arterial re-infusion flow rates and should be weighed against the hazards of increased venous air aspiration and blood product requirements.
Keywords
Adolescent, Adult, Arteries/physiology, Cardiopulmonary Bypass/methods, Drainage/methods, Erythrocyte Count, Female, Heart Failure/physiopathology, Heart Failure/surgery, Heart Transplantation/methods, Heart-Assist Devices/standards, Humans, Kinetics, Male, Middle Aged, Regional Blood Flow, Reoperation/adverse effects, Sternum/surgery, Young Adult
Pubmed
Web of science
Open Access
Yes
Create date
29/03/2019 7:22
Last modification date
20/08/2019 14:55
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