Contrasting patterns of sequence divergence and base composition between Drosophila introns and intergenic regions.

Détails

ID Serval
serval:BIB_92070CC24CE2
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Contrasting patterns of sequence divergence and base composition between Drosophila introns and intergenic regions.
Périodique
Biology Letters
Auteur(s)
Ometto L., De Lorenzo D., Stephan W.
ISSN
1744-9561
Statut éditorial
Publié
Date de publication
2006
Peer-reviewed
Oui
Volume
2
Numéro
4
Pages
604-607
Langue
anglais
Résumé
Two non-coding DNA classes, introns and intergenic regions, of Drosophila melanogaster exhibit contrasting evolutionary patterns. GC content is significantly higher in intergenic regions and affects their degree of nucleotide variability. Divergence is positively correlated with recombination rate in intergenic regions, but not in introns. We argue that these differences are due to different selective constraints rather than mutational or recombinational mechanisms.
Mots-clé
Animals, Base Composition/genetics, DNA, Intergenic/genetics, Drosophila/genetics, Evolution, Molecular, Genetic Variation, Introns/genetics, Mutation/genetics, Sequence Analysis, DNA/veterinary, Statistics as Topic
Pubmed
Web of science
Création de la notice
19/11/2007 11:40
Dernière modification de la notice
03/03/2018 19:30
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