Clonal analysis of the BALB/c T cell proliferative response to apo beef cytochrome c.
Details
Serval ID
serval:BIB_91C725E54215
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Clonal analysis of the BALB/c T cell proliferative response to apo beef cytochrome c.
Journal
Journal of Immunology
ISSN
0022-1767 (Print)
ISSN-L
0022-1767
Publication state
Published
Issued date
1981
Volume
127
Number
6
Pages
2442-2446
Language
english
Abstract
Murine T cell clones that proliferated specifically in response to the protein antigen apo cytochrome c were derived and maintained in continuous culture. Two distinct clonotypes were observed with respect to the proliferative responses observed when a variety of peptides prepared from several species of cytochrome c were tested. These 2 clonotypes appeared to recognize 2 different regions in the cytochrome c molecule. Only 1 of the 2 clonotypes tested demonstrated helper cell activity for antibody formation in vitro.
Keywords
Animals, Antibody Formation, Antibody-Producing Cells/immunology, Apoproteins/immunology, Cattle, Clone Cells/immunology, Cytochrome c Group/pharmacology, Hemolytic Plaque Technique, Horses, Lymph Nodes/immunology, Lymphocyte Activation, Mice, Mice, Inbred BALB C, T-Lymphocytes/immunology, Trinitrobenzenes/immunology
Pubmed
Web of science
Create date
24/01/2008 15:55
Last modification date
20/08/2019 15:54
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