Umbilical cord length in Down's syndrome

Détails

ID Serval
serval:BIB_90BCD8CF1B86
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Umbilical cord length in Down's syndrome
Périodique
American Journal of Diseases of Children
Auteur(s)
Moessinger  A. C., Mills  J. L., Harley  E. E., Ramakrishnan  R., Berendes  H. W., Blanc  W. A.
ISSN
0002-922X (Print)
Statut éditorial
Publié
Date de publication
12/1986
Volume
140
Numéro
12
Pages
1276-7
Notes
Journal Article --- Old month value: Dec
Résumé
Fetal motor activity is believed to influence umbilical cord growth. As Down's syndrome is associated with hypotonicity and reduced fetal activity, we hypothesized that newborn infants with this syndrome have short umbilical cords. We identified 21 infants with Down's syndrome and compared each individual cord length to mean standard values derived from the same population and matched for sex, race, and gestational age. Infants with Down's syndrome were found to have significantly shorter umbilical cords (mean of 45.1 cm compared with 57.3 cm for matched standards). It is not clear whether their cords are shorter on the basis of decreased fetal activity, genetics, or both. If it is on the basis of decreased fetal activity, it would be interesting to see if those with the shortest cords (presumed to have been the most hypoactive in utero) could be predicted to have worse neurodevelopmental outcomes.
Mots-clé
Down Syndrome/*diagnosis Female Humans Infant, Newborn Pregnancy Reference Values Umbilical Cord/*pathology
Pubmed
Web of science
Création de la notice
25/01/2008 14:16
Dernière modification de la notice
03/03/2018 19:26
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