THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview.

Détails

Ressource 1Télécharger: 29055037_BIB_8FEEA9D783AA.pdf (460.03 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_8FEEA9D783AA
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview.
Périodique
British journal of pharmacology
Auteur(s)
Alexander S.P., Kelly E., Marrion N.V., Peters J.A., Faccenda E., Harding S.D., Pawson A.J., Sharman J.L., Southan C., Buneman O.P., Cidlowski J.A., Christopoulos A., Davenport A.P., Fabbro D., Spedding M., Striessnig J., Davies J.A.
Collaborateur(s)
CGTP Collaborators
Contributeur(s)
Abbracchio M.P., Aldrich R., Al-Hosaini K., Arumugam T.V., Attali B., Bäck M., Barnes N.M., Bathgate R., Beart P.M., Becirovic E., Bettler B., Biel M., Birdsall N.J., Blaho V., Boison D., Bräuner-Osborne H., Bröer S., Bryant C., Burnstock G., Calo G., Catterall W.A., Ceruti S., Chan S.L., Chandy K.G., Chazot P., Chiang N., Chun J.J., Chung J.J., Clapham D.E., Clapp L., Connor M.A., Cox H.M., Davies P., Dawson P.A., Decaen P., Dent G., Doherty P., Douglas S.D., Dubocovich M.L., Fong T.M., Fowler C.J., Frantz A., Fuller P., Fumagalli M., Futerman A.H., Gainetdinov R.R., Gershengorn M.A., Goldin A., Goldstein S., Goudet C., Gregory K., Grissmer S., Gundlach A.L., Hagenbuch B., Hamann J., Hammond J.R., Hancox J.C., Hanson J., Hanukoglu I., Hay D.L., Hobbs A.J., Hollenberg A.N., Holliday N.D., Hoyer D., Ijzerman A.P., Inui K.I., Irving A.J., Ishii S., Jacobson K.A., Jan L.Y., Jarvis M.F., Jensen R., Jockers R., Kaczmarek L.K., Kanai Y., Karnik S., Kellenberger S., Kemp S., Kennedy C., Kerr I.D., Kihara Y., Kukkonen J., Larhammar D., Leach K., Lecca D., Leeman S., Leprince J., Lolait S.J., Macewan D., Maguire J.J., Marshall F., Mazella J., Mcardle C.A., Michel M.C., Miller L.J., Mitolo V., Mizuno H., Monk P.N., Mouillac B., Murphy P.M., Nahon J.L., Nerbonne J., Nichols C.G., Norel X., Offermanns S., Palmer L.G., Panaro M.A., Papapetropoulos A., Perez-Reyes E., Pertwee R.G., Pintor S., Pisegna J.R., Plant L.D., Poyner D.R., Prossnitz E.R., Pyne S., Ramachandran R., Ren D., Rondard P., Ruzza C., Sackin H., Sanger G., Sanguinetti M.C., Schild L., Schiöth H., Schulte G., Schulz S., Segaloff D.L., Serhan C.N., Singh K.D., Slesinger P.A., Snutch T.P., Sobey C.G., Stewart G., Stoddart L.A., Summers R.J., Szabo C., Thwaites D., Toll L., Trimmer J.S., Tucker S., Vaudry H., Verri T., Vilargada J.P., Waldman S.A., Ward D.T., Waxman S.G., Wei A.D., Willars G.B., Wong S.S., Woodruff T.M., Wulff H., Ye R.D., Yung Y., Zajac J.M.
ISSN
1476-5381 (Electronic)
ISSN-L
0007-1188
Statut éditorial
Publié
Date de publication
12/2017
Peer-reviewed
Oui
Volume
174 Suppl 1
Pages
S1-S16
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13882/full. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
Mots-clé
Databases, Pharmaceutical, Humans, Knowledge Bases, Ligands, Proteins
Pubmed
Web of science
Open Access
Oui
Création de la notice
12/02/2019 8:36
Dernière modification de la notice
21/08/2019 6:09
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