Le traitement des melanomes exteriorises de la choroide par faisceau de protons acceleres. [Treatment of exterior extension of choroid melanomas by accelerated proton beams]

Détails

ID Serval
serval:BIB_8FB06C8DC6B2
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Le traitement des melanomes exteriorises de la choroide par faisceau de protons acceleres. [Treatment of exterior extension of choroid melanomas by accelerated proton beams]
Périodique
Klinische Monatsblatter fur Augenheilkunde
Auteur(s)
Bercher  L., Zografos  L., Egger  E., Chamot  L., Uffer  S., Gailloud  C., Ducrey  N.
ISSN
0023-2165 (Print)
Statut éditorial
Publié
Date de publication
05/1992
Volume
200
Numéro
5
Pages
440-3
Notes
English Abstract
Journal Article --- Old month value: May
Résumé
Among the 934 patients with a choroidal melanoma treated in first intention with an accelerated proton beam since 1984, 41 (4.4%) presented an extrascleral extension, of which 11 were located anteriorly and 30 posteriorly. For these 30 cases, the diagnosis was made by B ultrasonography only when the volume of the extension was important, between 20 and 2280 mm3. The Cox model multi-variant analysis was used to study the statistically significant parameters in the development of an extrascleral extension. It appears that the maximal diameter of the intraocular tumor (p = 0.0012), the localisation of the anterior margin (p = 0.0304) and the age of the patients (p = 0.0097) are statistically meaningful. The 4 years' survival, studied with the Kaplan-Meier curves, is estimated at 60% for the patients with extrascleral extension and at 85% for the patients without. These results are similar to those of literature, whatever treatment is chosen (enucleation and radiotherapy, exenteration).
Mots-clé
Adult Aged Aged, 80 and over Choroid Neoplasms/pathology/*radiotherapy Female Follow-Up Studies Humans Male Melanoma/pathology/*radiotherapy Middle Aged Neoplasm Recurrence, Local/pathology/radiotherapy Neoplasm Staging Protons Radiotherapy Dosage
Pubmed
Web of science
Création de la notice
28/01/2008 14:10
Dernière modification de la notice
03/03/2018 19:22
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