Combined functional and viability cardiac MR imaging in a single breathhold
Details
Serval ID
serval:BIB_8F8832D06C3A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Combined functional and viability cardiac MR imaging in a single breathhold
Journal
Magnetic Resonance in Medicine
ISSN
0740-3194
Publication state
Published
Issued date
2007
Peer-reviewed
Oui
Volume
58
Number
4
Pages
843-849
Language
english
Notes
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, Non-U.S. Gov't
Abstract
The combination of cardiac viability and functional information enhances the identification of different heart tissues in the setting of ischemic heart disease. A method has recently been proposed for obtaining black-blood delayed-enhancement (DE) viability images using the stimulated-echo acquisition mode (STEAM) MRI pulse sequence in a single short breathhold. The method was validated against conventional inversion-recovery (IR) DE images for identifying regions of myocardial infarction (MI). The method was based on the acquisition of three consecutive images of the same anatomical slice. One image has T(1)-weighted contrast in which infarction appears bright. The two other images are used to construct an anatomical image of the heart, which is combined with the first image to produce a black-blood viability image. However, using appropriate modulation and demodulation frequencies, the latter two images bear useful information about myocardial deformation that results in a cardiac strain-encoding (SENC) functional image. In this work, a method is proposed for obtaining three consecutive SENC images in a single acquisition that can be combined to produce a composite image of the heart, which shows both functional and viability information. The proposed technique reduces scan time by one-half, compared with separate acquisitions of functional and viability images, and alleviates misregistration problems caused by separate breathholds.
Keywords
Animals, Coronary Vessels, Dogs, *Heart/physiology, Magnetic Resonance Imaging/*methods, Myocardial Infarction/diagnosis, Phantoms, Imaging, Tissue Survival
Pubmed
Web of science
Create date
02/03/2010 16:04
Last modification date
20/08/2019 14:53