Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
TRANSITION IN ENDOCRINOLOGY: Hypogonadism in adolescence.
European Journal of Endocrinology
Publication types: Journal Article ; ReviewPublication Status: ppublishDocument Type: Review
Puberty is a remarkable developmental process with the activation of the hypothalamic-pituitary-gonadal axis culminating in reproductive capacity. It is accompanied by cognitive, psychological, emotional, and sociocultural changes. There is wide variation in the timing of pubertal onset, and this process is affected by genetic and environmental influences. Disrupted puberty (delayed or absent) leading to hypogonadism may be caused by congenital or acquired etiologies and can have significant impact on both physical and psychosocial well-being. While adolescence is a time of growing autonomy and independence, it is also a time of vulnerability and thus, the impact of hypogonadism can have lasting effects. This review highlights the various forms of hypogonadism in adolescence and the clinical challenges in differentiating normal variants of puberty from pathological states. In addition, hormonal treatment, concerns regarding fertility, emotional support, and effective transition to adult care are discussed.
Adolescent, Female, Humans, Hypogonadism/epidemiology, Hypogonadism/psychology, Male, Puberty, Delayed/complications, Puberty, Delayed/physiopathology, Puberty, Precocious/complications, Puberty, Precocious/physiopathology
Web of science
Last modification date