Identification of HIV integration sites in infected host genomic DNA.

Détails

Ressource 1Télécharger: BIB_8EED600CB038.P001.pdf (544.49 [Ko])
Etat: Serval
Version: Author's accepted manuscript
ID Serval
serval:BIB_8EED600CB038
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Identification of HIV integration sites in infected host genomic DNA.
Périodique
Methods
Auteur(s)
Ciuffi A., Barr S.D.
ISSN
1095-9130 (Electronic)
ISSN-L
1046-2023
Statut éditorial
Publié
Date de publication
2011
Peer-reviewed
Oui
Volume
53
Numéro
1
Pages
39-46
Langue
anglais
Résumé
The integration of the Human Immunodeficiency Virus (HIV) genetic information into the host genome is fundamental for its replication and long-term persistence in the host. Isolating and characterizing the integration sites can be useful for obtaining data such as identifying the specific genomic location of integration or understanding the forces dictating HIV integration site selection. The methods outlined in this article describe a highly efficient and precise technique for identifying HIV integration sites in the host genome on a small scale using molecular cloning techniques and standard sequencing or on a massive scale using 454 pyrosequencing.
Pubmed
Web of science
Open Access
Oui
Création de la notice
06/04/2011 10:49
Dernière modification de la notice
08/05/2019 21:53
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