Efficacite et tolerance de la cyclosporine A dans le traitement de la sclerose en plaques. [Efficacy and tolerance of cyclosporin A in the treatment of multiple sclerosis]
Details
Serval ID
serval:BIB_8E90FCFFBDF5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Efficacite et tolerance de la cyclosporine A dans le traitement de la sclerose en plaques. [Efficacy and tolerance of cyclosporin A in the treatment of multiple sclerosis]
Journal
Schweizerische Rundschau fur Medizin Praxis
ISSN
1013-2058 (Print)
Publication state
Published
Issued date
06/1991
Volume
80
Number
24
Pages
670-2
Notes
Clinical Trial
Comparative Study
English Abstract
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't --- Old month value: Jun 11
Comparative Study
English Abstract
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't --- Old month value: Jun 11
Abstract
The use and tolerance of cyclosporine A (Cy A) and azathioprine (AZA) are compared as long-term immunosuppression treatment for multiple sclerosis. 38 patients with multiple sclerosis were randomized and received either Cy A (5 mg/kg/d) or AZA (2 mg/kg/d) during 24 months. These patients were assessed clinically and with different biological parameters. The Cy A blood level was controlled, and Cy A was well tolerated without side effects forcing to stop the treatment. However, its benefits were limited when the different clinical scores are compared.
Keywords
Adult
Azathioprine/adverse effects/*therapeutic use
Cyclosporins/adverse effects/*therapeutic use
Humans
Middle Aged
Multiple Sclerosis/*drug therapy
Pubmed
Create date
25/01/2008 13:46
Last modification date
20/08/2019 15:52
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