The Human Vaccines Project: A roadmap for cancer vaccine development.

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Serval ID
serval:BIB_8E2A78076655
Type
Article: article from journal or magazin.
Collection
Publications
Institution
UNIL/CHUV
Title
The Human Vaccines Project: A roadmap for cancer vaccine development.
Journal
Science translational medicine
Author(s)
Romero P., Banchereau J., Bhardwaj N., Cockett M., Disis M.L., Dranoff G., Gilboa E., Hammond S.A., Hershberg R., Korman A.J., Kvistborg P., Melief C., Mellman I., Palucka A.K., Redchenko I., Robins H., Sallusto F., Schenkelberg T., Schoenberger S., Sosman J., Türeci Ö., Van den Eynde B., Koff W., Coukos G.
ISSN
1946-6242 (Electronic)
ISSN-L
1946-6234
Publication state
Published
Issued date
13/04/2016
Peer-reviewed
Oui
Volume
8
Number
334
Pages
334ps9
Language
english
Notes
Publication types: Journal Article ; Review Publication Status: ppublish
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review

Abstract
Cancer vaccine development has been vigorously pursued for 40 years. Immunity to tumor antigens can be elicited by most vaccines tested, but their clinical efficacy remains modest. We argue that a concerted international effort is necessary to understand the human antitumor immune response and achieve clinically effective cancer vaccines.

Keywords
Antigens, Neoplasm/immunology, Cancer Vaccines/immunology, Humans, Immunologic Memory, T-Lymphocytes/immunology
OAI-PMH
oai:serval.unil.ch:BIB_8E2A78076655
DOI
10.1126/scitranslmed.aaf0685
Pubmed
27075624
Create date
03/05/2016 17:04
Last modification date
20/08/2019 14:52
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